Cell culture-derived influenza vaccines in the severe 2017-2018 epidemic season: a step towards improved influenza vaccine effectiveness.

The 2017-2018 seasonal influenza epidemics are severe in the US and Australia where A (H3N2) virus subtype dominated. Although circulating A (H3N2) virus antigen is not different from that recommended by the WHO for vaccine production, the overall interim estimate of vaccine effectiveness was under the historical average (33%) for A (H3N2) virus. The majority (USA) or all (Australia) dose of vaccine contains several amino acid changes in the hemagglutinin protein, which is produced from the necessary adaptation of the virus to embryonated chicken eggs used to manufacture the vaccine most. Previous reports have suggested the potential negative impact of the substitution of egg-driven performance of the vaccine. With the support of Barda, two vaccines licensed in the US is produced in cell culture: a recombinant influenza vaccine (RIV, Flublok ™) produced in insect cells and inactivated vaccines adult mammalian cells (ccIIV, Flucelvax ™). CcIIV quadrivalent (ccIIV4) vaccine for the 2017-2018 influenza season was produced using seed virus A (H3N2) distributed exclusively in cell culture and therefore less adaptative changes eggs. ccIIV dose fairly distributed (but not RIV dose) to allow the initial estimates of higher efficacy relative to traditional egg-based vaccine, the study details pending. The increased availability of certain product comparison vaccine effectiveness estimates for cell-based vaccine and egg-based can provide important clues to inform vaccine product improvements moving forward.

Diclofenac Diethylamine
B1928-50	ApexBio	50 mg	EUR 128.00
Description: Diclofenac diethylamine is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.

Diclofenac Diethylamine
B1928-S	ApexBio	Evaluation Sample	EUR 81.00
Description: Diclofenac diethylamine is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.

Diclofenac (diethylamine)
HY-15036A	MedChemExpress	10mM/1mL	EUR 113.00

Diclofenac diethylamine
20-abx185392	Abbexa	EUR 425.00 EUR 244.00	0 1
Shipped within 1-2 weeks.

Stachydrine (hydrochloride)
C3648-100	ApexBio	100 mg	EUR 119.00
Description: Stachydrine is an anti-metastatic agent.Stachydrine, a pyrrolidine betaine, was first isolated from seed husk and the pulp of the fruit of C. Leonurus, and many other Asian plants and fruits.

Stachydrine (hydrochloride)
C3648-1000	ApexBio	1 g	EUR 467.00
Description: Stachydrine is an anti-metastatic agent.Stachydrine, a pyrrolidine betaine, was first isolated from seed husk and the pulp of the fruit of C. Leonurus, and many other Asian plants and fruits.

Stachydrine (hydrochloride)
C3648-250	ApexBio	250 mg	EUR 206.00
Description: Stachydrine is an anti-metastatic agent.Stachydrine, a pyrrolidine betaine, was first isolated from seed husk and the pulp of the fruit of C. Leonurus, and many other Asian plants and fruits.

Stachydrine (hydrochloride)
C3648-500	ApexBio	500 mg	EUR 328.00
Description: Stachydrine is an anti-metastatic agent.Stachydrine, a pyrrolidine betaine, was first isolated from seed husk and the pulp of the fruit of C. Leonurus, and many other Asian plants and fruits.

Barnidipine (hydrochloride)
C3727-100	ApexBio	100 mg	EUR 203.00
Description: Barnidipine is a calcium-channel blocker.A calcium channel, an ion channel which displays selective permeability to calcium ions, is sometimes synonymous as voltage-dependent calcium channel, although there are also ligand-gated calcium channels.

Barnidipine (hydrochloride)
C3727-50	ApexBio	50 mg	EUR 155.00
Description: Barnidipine is a calcium-channel blocker.A calcium channel, an ion channel which displays selective permeability to calcium ions, is sometimes synonymous as voltage-dependent calcium channel, although there are also ligand-gated calcium channels.

MS049 (hydrochloride)
C3776-10	ApexBio	10 mg	EUR 200.00
Description: IC50: 34 nM for PRMT4; 43 nM for PRMT6 MS049 is a dual PRMT4 and PRMT6 inhibitor.

MS049 (hydrochloride)
C3776-100	ApexBio	100 mg	EUR 1181.00
Description: IC50: 34 nM for PRMT4; 43 nM for PRMT6 MS049 is a dual PRMT4 and PRMT6 inhibitor.

MS049 (hydrochloride)
C3776-25	ApexBio	25 mg	EUR 382.00
Description: IC50: 34 nM for PRMT4; 43 nM for PRMT6 MS049 is a dual PRMT4 and PRMT6 inhibitor.

MS049 (hydrochloride)
C3776-5	ApexBio	5 mg	EUR 139.00
Description: IC50: 34 nM for PRMT4; 43 nM for PRMT6 MS049 is a dual PRMT4 and PRMT6 inhibitor.

MS049 (hydrochloride)
C3776-5.1	ApexBio	10 mM (in 1mL DMSO)	EUR 150.00
Description: IC50: 34 nM for PRMT4; 43 nM for PRMT6 MS049 is a dual PRMT4 and PRMT6 inhibitor.

MS049 (hydrochloride)
C3776-50	ApexBio	50 mg	EUR 653.00
Description: IC50: 34 nM for PRMT4; 43 nM for PRMT6 MS049 is a dual PRMT4 and PRMT6 inhibitor.

Guanabenz (hydrochloride)
C3786-100	ApexBio	100 mg	EUR 231.00
Description: Guanabenz is an orally active ?2-adrenoceptor agonist with hypotensive effects [1]. The ?2 adrenergic receptors belong to a family of G protein-coupled receptor (GPCR), mediate many physiological actions of the endogenous catecholamines adrenaline and noradrenaline.

Guanabenz (hydrochloride)
C3786-50	ApexBio	50 mg	EUR 144.00
Description: Guanabenz is an orally active ?2-adrenoceptor agonist with hypotensive effects [1]. The ?2 adrenergic receptors belong to a family of G protein-coupled receptor (GPCR), mediate many physiological actions of the endogenous catecholamines adrenaline and noradrenaline.

Ulixertinib (hydrochloride)
C3921-10	ApexBio	10 mg	EUR 406.00
Description: Ulixertinib, also named as BVD-523, is a novel and reversible inhibitor of ERK1/2. Ulixertinib potently and selectively inhibits the activity of ERK1 and ERK2 kinases in a reversible, ATP-competitive fashion [1].

Ulixertinib (hydrochloride)
C3921-25	ApexBio	25 mg	EUR 661.00
Description: Ulixertinib, also named as BVD-523, is a novel and reversible inhibitor of ERK1/2. Ulixertinib potently and selectively inhibits the activity of ERK1 and ERK2 kinases in a reversible, ATP-competitive fashion [1].

Ulixertinib (hydrochloride)
C3921-5	ApexBio	5 mg	EUR 250.00
Description: Ulixertinib, also named as BVD-523, is a novel and reversible inhibitor of ERK1/2. Ulixertinib potently and selectively inhibits the activity of ERK1 and ERK2 kinases in a reversible, ATP-competitive fashion [1].

Chlorcyclizine (hydrochloride)
C3989-100	ApexBio	100 mg	EUR 118.00
Description: Chlorcyclizine is a phenylpiperazine antagonist for histamine H1 receptor [1]. The histamine has been involved in modulating many physiological functions of the hypothalamus, such as arousal state, feeding, locomotor activity, and drinking.

Chlorcyclizine (hydrochloride)
C3989-1000	ApexBio	1 g	EUR 595.00
Description: Chlorcyclizine is a phenylpiperazine antagonist for histamine H1 receptor [1]. The histamine has been involved in modulating many physiological functions of the hypothalamus, such as arousal state, feeding, locomotor activity, and drinking.

Chlorcyclizine (hydrochloride)
C3989-250	ApexBio	250 mg	EUR 210.00
Description: Chlorcyclizine is a phenylpiperazine antagonist for histamine H1 receptor [1]. The histamine has been involved in modulating many physiological functions of the hypothalamus, such as arousal state, feeding, locomotor activity, and drinking.

Chlorcyclizine (hydrochloride)
C3989-500	ApexBio	500 mg	EUR 357.00
Description: Chlorcyclizine is a phenylpiperazine antagonist for histamine H1 receptor [1]. The histamine has been involved in modulating many physiological functions of the hypothalamus, such as arousal state, feeding, locomotor activity, and drinking.

Lofexidine (hydrochloride)
C3990-1000	ApexBio	1 g	EUR 126.00
Description: Lofexidine is a ?2-Receptor agonist for opioid detoxification. Lofexidine shows a strong affinity for the ?2A-receptor subtype [1].

Lofexidine (hydrochloride)
C3990-5.1	ApexBio	10 mM (in 1mL H2O)	EUR 113.00
Description: Lofexidine is a ?2-Receptor agonist for opioid detoxification. Lofexidine shows a strong affinity for the ?2A-receptor subtype [1].

Lofexidine (hydrochloride)
C3990-500	ApexBio	500 mg	EUR 100.00
Description: Lofexidine is a ?2-Receptor agonist for opioid detoxification. Lofexidine shows a strong affinity for the ?2A-receptor subtype [1].

Nortriptyline (hydrochloride)
C4077-100	ApexBio	100 mg	EUR 163.00
Description: Ki: 3.4 nM: blocks the norepinephrine transporter.Ki: 161 nM: inhibits the serotonin transporter.

Nortriptyline (hydrochloride)
C4077-5.1	ApexBio	10 mM (in 1mL DMSO)	EUR 113.00
Description: Ki: 3.4 nM: blocks the norepinephrine transporter.Ki: 161 nM: inhibits the serotonin transporter.

Nortriptyline (hydrochloride)
C4077-50	ApexBio	50 mg	EUR 116.00
Description: Ki: 3.4 nM: blocks the norepinephrine transporter.Ki: 161 nM: inhibits the serotonin transporter.

Imipramine (hydrochloride)
C4117-5.1	ApexBio	10 mM (in 1mL H2O)	EUR 113.00
Description: Imipramine (hydrochloride) is a tricyclic antidepressant and is mainly used in the treatment of major depression and enuresis [1]. Antidepressants are antagonists of many neurotransmitter receptors in human brain [3].

Imipramine (hydrochloride)
C4117-5000	ApexBio	5 g	EUR 108.00
Description: Imipramine (hydrochloride) is a tricyclic antidepressant and is mainly used in the treatment of major depression and enuresis [1]. Antidepressants are antagonists of many neurotransmitter receptors in human brain [3].

Clorgyline (hydrochloride)
C4137-100	ApexBio	100 mg	EUR 224.00
Description: Clorgyline (hydrochloride) is an irreversible, potent and selective monoamine oxidase (MAO) A inhibitor with Ki values of 0.054 and 58 ?M and IC50 values of 0.0012 and 1.9 ?M for MAO-A and MAO-B, respectively [1][2].

Clorgyline (hydrochloride)
C4137-25	ApexBio	25 mg	EUR 110.00
Description: Clorgyline (hydrochloride) is an irreversible, potent and selective monoamine oxidase (MAO) A inhibitor with Ki values of 0.054 and 58 ?M and IC50 values of 0.0012 and 1.9 ?M for MAO-A and MAO-B, respectively [1][2].

Clorgyline (hydrochloride)
C4137-50	ApexBio	50 mg	EUR 154.00
Description: Clorgyline (hydrochloride) is an irreversible, potent and selective monoamine oxidase (MAO) A inhibitor with Ki values of 0.054 and 58 ?M and IC50 values of 0.0012 and 1.9 ?M for MAO-A and MAO-B, respectively [1][2].

Doxepin (hydrochloride)
C4153-5.1	ApexBio	10 mM (in 1mL DMSO)	EUR 113.00
Description: Doxepin, a tricyclic antidepressant, is a potent histamine H1 antagonist [1]. The histamine receptors belong to a family of G protein?coupled receptors activated by their primary endogenous ligand histamine.

Doxepin (hydrochloride)
C4153-5000	ApexBio	5 g	EUR 168.00
Description: Doxepin, a tricyclic antidepressant, is a potent histamine H1 antagonist [1]. The histamine receptors belong to a family of G protein?coupled receptors activated by their primary endogenous ligand histamine.

Anhydrochlortetracycline (hydrochloride)
C4218-1	ApexBio	1 mg	EUR 132.00
Description: Anhydrochlortetracycline was produced by the acid degradation of chlortetracycline. Anhydrochlortetracycline only have a fraction of the antibacterial activity of chlortetracycline. Anhydrochlortetracycline strongly inhibited the growth of Streptomyces aureofaciem.

Anhydrochlortetracycline (hydrochloride)
C4218-5	ApexBio	5 mg	EUR 255.00
Description: Anhydrochlortetracycline was produced by the acid degradation of chlortetracycline. Anhydrochlortetracycline only have a fraction of the antibacterial activity of chlortetracycline. Anhydrochlortetracycline strongly inhibited the growth of Streptomyces aureofaciem.

Anhydrotetracycline (hydrochloride)
C4291-100	ApexBio	100 mg	EUR 241.00
Description: Anhydrotetracycline (hydrochloride) (ATC) is a powerful effector for the tetracycline repressor (TetR) and reverse tetracycline repressor (revTetR) systems [1].

Anhydrotetracycline (hydrochloride)
C4291-25	ApexBio	25 mg	EUR 123.00
Description: Anhydrotetracycline (hydrochloride) (ATC) is a powerful effector for the tetracycline repressor (TetR) and reverse tetracycline repressor (revTetR) systems [1].

Anhydrotetracycline (hydrochloride)
C4291-50	ApexBio	50 mg	EUR 171.00
Description: Anhydrotetracycline (hydrochloride) (ATC) is a powerful effector for the tetracycline repressor (TetR) and reverse tetracycline repressor (revTetR) systems [1].

(±)-Salsolinol (hydrochloride)
C4364-500	ApexBio	500 mg	EUR 308.00
Description: (±)-Salsolinol targets depolarize dopamineric neurons. Dopaminergic neurons produce dopamine, a neurotransmitter with various roles in neurological functions.

Midodrine (hydrochloride)
C4493-100	ApexBio	100 mg	EUR 113.00
Description: Ki: 2, 6.9, and 1.7 ?M for ?1A, ?1B, ?1D, respectivelyMidodrine is the prodrug of the ?1-adrenergic receptor agonist, 1-(2?,5?-dimethoxyphenyl)-2-aminoethanol.

Midodrine (hydrochloride)
C4493-250	ApexBio	250 mg	EUR 200.00
Description: Ki: 2, 6.9, and 1.7 ?M for ?1A, ?1B, ?1D, respectivelyMidodrine is the prodrug of the ?1-adrenergic receptor agonist, 1-(2?,5?-dimethoxyphenyl)-2-aminoethanol.

Celiprolol (hydrochloride)
C4521-10	ApexBio	10 mg	EUR 254.00
Description: Celiprolol is a ?1 adrenergic receptor antagonist and ?2 adrenergic receptor partial agonist.?2 adrenergic receptor agonists, also known as adrenergic ?2 receptor agonists, are a class of drugs acting on the ?2 adrenergic receptor.

Celiprolol (hydrochloride)
C4521-25	ApexBio	25 mg	EUR 500.00
Description: Celiprolol is a ?1 adrenergic receptor antagonist and ?2 adrenergic receptor partial agonist.?2 adrenergic receptor agonists, also known as adrenergic ?2 receptor agonists, are a class of drugs acting on the ?2 adrenergic receptor.

Celiprolol (hydrochloride)
C4521-5	ApexBio	5 mg	EUR 183.00
Description: Celiprolol is a ?1 adrenergic receptor antagonist and ?2 adrenergic receptor partial agonist.?2 adrenergic receptor agonists, also known as adrenergic ?2 receptor agonists, are a class of drugs acting on the ?2 adrenergic receptor.

Aceclidine (hydrochloride)
C4635-1000	ApexBio	1 g	EUR 328.00

Aceclidine (hydrochloride)
C4635-500	ApexBio	500 mg	EUR 206.00

Trimidox (hydrochloride)
C4714-10	ApexBio	10 mg	EUR 184.00
Description: Trimidox (hydrochloride) is a specific ribonucleotide reductase inhibitor [1][2][3]. Ribonucleotide reductase is the rate-limiting enzyme for de novo DNA synthesis.

Trimidox (hydrochloride)
C4714-25	ApexBio	25 mg	EUR 370.00
Description: Trimidox (hydrochloride) is a specific ribonucleotide reductase inhibitor [1][2][3]. Ribonucleotide reductase is the rate-limiting enzyme for de novo DNA synthesis.

Trimidox (hydrochloride)
C4714-5	ApexBio	5 mg	EUR 121.00
Description: Trimidox (hydrochloride) is a specific ribonucleotide reductase inhibitor [1][2][3]. Ribonucleotide reductase is the rate-limiting enzyme for de novo DNA synthesis.

Trimidox (hydrochloride)
C4714-50	ApexBio	50 mg	EUR 618.00
Description: Trimidox (hydrochloride) is a specific ribonucleotide reductase inhibitor [1][2][3]. Ribonucleotide reductase is the rate-limiting enzyme for de novo DNA synthesis.

Cycloguanil (hydrochloride)
C5763-10	ApexBio	10 mg	EUR 109.00
Description: Cycloguanil is an inhibitor of dihydrofolate reductase (DHFR)[1].Dihydrofolate reductase (DHFR) is an enzyme that involved in reducing dihydrofolic acid to tetrahydrofolic acid.

Cycloguanil (hydrochloride)
C5763-25	ApexBio	25 mg	EUR 163.00
Description: Cycloguanil is an inhibitor of dihydrofolate reductase (DHFR)[1].Dihydrofolate reductase (DHFR) is an enzyme that involved in reducing dihydrofolic acid to tetrahydrofolic acid.

Cycloguanil (hydrochloride)
C5763-50	ApexBio	50 mg	EUR 206.00
Description: Cycloguanil is an inhibitor of dihydrofolate reductase (DHFR)[1].Dihydrofolate reductase (DHFR) is an enzyme that involved in reducing dihydrofolic acid to tetrahydrofolic acid.

VU590 (hydrochloride)
C4778-10	ApexBio	10 mg	EUR 195.00

VU590 (hydrochloride)
C4778-25	ApexBio	25 mg	EUR 389.00

VU590 (hydrochloride)
C4778-5	ApexBio	5 mg	EUR 139.00

Bufuralol (hydrochloride)
C5043-1	ApexBio	1 mg	EUR 139.00
Description: Bufuralol is a non-specific ?-adrenergic blocker. Beta adrenergic agonists are medications relaxing muscles of the airways, which widens the airways and leads to easier breathing.

Bufuralol (hydrochloride)
C5043-10	ApexBio	10 mg	EUR 628.00
Description: Bufuralol is a non-specific ?-adrenergic blocker. Beta adrenergic agonists are medications relaxing muscles of the airways, which widens the airways and leads to easier breathing.

Bufuralol (hydrochloride)
C5043-5	ApexBio	5 mg	EUR 457.00
Description: Bufuralol is a non-specific ?-adrenergic blocker. Beta adrenergic agonists are medications relaxing muscles of the airways, which widens the airways and leads to easier breathing.

AN3365 (hydrochloride)
C5068-10	ApexBio	10 mg	EUR 328.00
Description: AN3365 is a potent and selective leucyl-tRNA synthetase inhibitor [1].The leucyl-tRNA synthetase belongs to a member of the class I aminoacyl-tRNA synthetase family.

AN3365 (hydrochloride)
C5068-25	ApexBio	25 mg	EUR 659.00
Description: AN3365 is a potent and selective leucyl-tRNA synthetase inhibitor [1].The leucyl-tRNA synthetase belongs to a member of the class I aminoacyl-tRNA synthetase family.

AN3365 (hydrochloride)
C5068-5	ApexBio	5 mg	EUR 206.00
Description: AN3365 is a potent and selective leucyl-tRNA synthetase inhibitor [1].The leucyl-tRNA synthetase belongs to a member of the class I aminoacyl-tRNA synthetase family.

Calindol (hydrochloride)
C5329-10	ApexBio	10 mg	EUR 440.00
Description: Calindol is an activator of the calcium-sensing receptor (CaSR).The extracellular calciumsensing receptor (CaSR), a G protein-coupled receptor (GPCR), senses extracellular calcium[Ca2+]e and regulates calciumion homeostasis.

Calindol (hydrochloride)
C5329-25	ApexBio	25 mg	EUR 902.00
Description: Calindol is an activator of the calcium-sensing receptor (CaSR).The extracellular calciumsensing receptor (CaSR), a G protein-coupled receptor (GPCR), senses extracellular calcium[Ca2+]e and regulates calciumion homeostasis.

Calindol (hydrochloride)
C5329-5	ApexBio	5 mg	EUR 270.00
Description: Calindol is an activator of the calcium-sensing receptor (CaSR).The extracellular calciumsensing receptor (CaSR), a G protein-coupled receptor (GPCR), senses extracellular calcium[Ca2+]e and regulates calciumion homeostasis.

Kasugamycin (hydrochloride)
C5503-10000	ApexBio	10 g	EUR 350.00
Description: Kasugamycin is an aminoglycosidic antibiotic. Aminoglycoside, a medicinal and bacteriologic category of traditional Gram-negative antibacterial therapeutic agent, inhibits protein synthesis and contains as a portion of the molecule an amino-modified glycoside.

Kasugamycin (hydrochloride)
C5503-5000	ApexBio	5 g	EUR 251.00
Description: Kasugamycin is an aminoglycosidic antibiotic. Aminoglycoside, a medicinal and bacteriologic category of traditional Gram-negative antibacterial therapeutic agent, inhibits protein synthesis and contains as a portion of the molecule an amino-modified glycoside.

Ciprofloxacin (hydrochloride)
C5539-10000	ApexBio	10 g	EUR 116.00
Description: Ciprofloxacin (hydrochloride) is a fluoroquinolone antibiotic that has antimicrobial and immunomodulatory activities [1].

Ciprofloxacin (hydrochloride)
C5539-25000	ApexBio	25 g	EUR 154.00
Description: Ciprofloxacin (hydrochloride) is a fluoroquinolone antibiotic that has antimicrobial and immunomodulatory activities [1].

Ciprofloxacin (hydrochloride)
C5539-50000	ApexBio	50 g	EUR 224.00
Description: Ciprofloxacin (hydrochloride) is a fluoroquinolone antibiotic that has antimicrobial and immunomodulatory activities [1].

Fendiline (hydrochloride)
C5675-5000	ApexBio	5 g	EUR 122.00
Description: Fendiline is an ?2-adrenergic receptor antagonist and L-type calcium channel blocker [1,2].The ?2 adrenergic receptor is a G protein-coupled receptor (GPCR). Until now, three different ?2-receptor subtypes have been identified: ?2A, ?2B, and ?2C.

Afuresertib hydrochloride
B1848-5	Biovision		EUR 175.00

Chlorpromazine hydrochloride
B1992-100	Biovision		EUR 120.00

Chlorpromazine hydrochloride
B1992-500	Biovision		EUR 294.00

Triflupromazine hydrochloride
B1993-100	Biovision		EUR 120.00

ZLN024 hydrochloride
B2034-25	Biovision		EUR 588.00

ZLN024 hydrochloride
B2034-5	Biovision		EUR 185.00

Topotecan hydrochloride
B2050-10	Biovision		EUR 131.00

Givinostat hydrochloride
B2081-25	Biovision		EUR 756.00

Givinostat hydrochloride
B2081-5	Biovision		EUR 229.00

Moexipril hydrochloride
B2134-25	Biovision		EUR 294.00

Imidapril hydrochloride
B2135-25	Biovision		EUR 414.00

Imidapril hydrochloride
B2135-5	Biovision		EUR 142.00

Benazepril hydrochloride
B2138-250	Biovision		EUR 294.00

Benazepril hydrochloride
B2138-50	Biovision		EUR 131.00

Dorzolamide hydrochloride
B2185-10	Biovision		EUR 120.00

Dorzolamide hydrochloride
B2185-50	Biovision		EUR 327.00

Eltoprazine hydrochloride
B2301-25	Biovision		EUR 457.00

Eltoprazine hydrochloride
B2301-5	Biovision		EUR 153.00

Papaverine hydrochloride
B2315-250	Biovision		EUR 262.00

Papaverine hydrochloride
B2315-50	Biovision		EUR 120.00

Sarecycline hydrochloride
B2383-25	Biovision		EUR 588.00

Sarecycline hydrochloride
B2383-5	Biovision		EUR 185.00

Sertraline (hydrochloride)
B2393-10	Biovision		EUR 131.00

Sertraline (hydrochloride)
B2393-50	Biovision		EUR 327.00

Migalastat hydrochloride
B2404-25	Biovision		EUR 756.00

Migalastat hydrochloride
B2404-5	Biovision		EUR 229.00

Butenafine hydrochloride
B2421-250	Biovision		EUR 327.00

Butenafine hydrochloride
B2421-50	Biovision		EUR 120.00

Naftifine hydrochloride
B2422-10	Biovision		EUR 131.00

Naftifine hydrochloride
B2422-50	Biovision		EUR 349.00

Rilpivirine hydrochloride
B2427-25	Biovision		EUR 414.00

Rilpivirine hydrochloride
B2427-5	Biovision		EUR 142.00

Tirabrutinib hydrochloride
B2556-25	Biovision		EUR 457.00

Tirabrutinib hydrochloride
B2556-5	Biovision		EUR 153.00

Robenidine hydrochloride
B2560-1G	Biovision		EUR 131.00

Robenidine hydrochloride
B2560-5G	Biovision		EUR 262.00

Sardomozide Hydrochloride
B2566-25	Biovision		EUR 631.00

Sardomozide Hydrochloride
B2566-5	Biovision		EUR 196.00

Riviciclib hydrochloride
B2567-1	Biovision		EUR 142.00

Riviciclib hydrochloride
B2567-5	Biovision		EUR 414.00

CPTH2 (hydrochloride)
B2815-1	Biovision		EUR 120.00

CPTH2 (hydrochloride)
B2815-5	Biovision		EUR 294.00

Resminostat (hydrochloride)
B2852-25	Biovision		EUR 588.00

Resminostat (hydrochloride)
B2852-5	Biovision		EUR 185.00

Almorexant hydrochloride
B3241-10	ApexBio	10 mg	EUR 440.00
Description: Almorexant is an antagonist of Orexin 1 receptor (OX1R) and Orexin 2 receptor (OX2R) with Kd values of 1.3nM and 0.17nM, respectively [1].

Almorexant hydrochloride
B3241-5	ApexBio	5 mg	EUR 270.00
Description: Almorexant is an antagonist of Orexin 1 receptor (OX1R) and Orexin 2 receptor (OX2R) with Kd values of 1.3nM and 0.17nM, respectively [1].

Memantine hydrochloride
B3308-200	ApexBio	200 mg	EUR 137.00
Description: Memantine hydrochloride is an antagonist of NMDA receptor with IC50 values of 0.93?M, 0.82?M and 0.47?M for NRIa/NR2A, NRIa/NR2B and NRIa/NR2D, respectively [1].

Memantine hydrochloride
B3308-5.1	ApexBio	10 mM (in 1mL DMSO)	EUR 113.00
Description: Memantine hydrochloride is an antagonist of NMDA receptor with IC50 values of 0.93?M, 0.82?M and 0.47?M for NRIa/NR2A, NRIa/NR2B and NRIa/NR2D, respectively [1].

Memantine hydrochloride
B3308-S	ApexBio	Evaluation Sample	EUR 81.00
Description: Memantine hydrochloride is an antagonist of NMDA receptor with IC50 values of 0.93?M, 0.82?M and 0.47?M for NRIa/NR2A, NRIa/NR2B and NRIa/NR2D, respectively [1].

Cyproheptadine hydrochloride
B3309-5.1	ApexBio	10 mM (in 1mL DMSO)	EUR 108.00
Description: Cyproheptadine hydrochloride is an antagonist of serotonin receptor [1]. Cyproheptadine is a serotonin and histamine antagonist as well as an antimuscarinic reagent.

Cyproheptadine hydrochloride
B3309-50	ApexBio	50 mg	EUR 128.00
Description: Cyproheptadine hydrochloride is an antagonist of serotonin receptor [1]. Cyproheptadine is a serotonin and histamine antagonist as well as an antimuscarinic reagent.

Cyproheptadine hydrochloride
B3309-S	ApexBio	Evaluation Sample	EUR 81.00
Description: Cyproheptadine hydrochloride is an antagonist of serotonin receptor [1]. Cyproheptadine is a serotonin and histamine antagonist as well as an antimuscarinic reagent.

Moxonidine hydrochloride
B3314-10	ApexBio	10 mg	EUR 195.00
Description: Moxonidine hydrochloride is a mixed agonist of ?2-adrenergic receptor (?2AR) and imidazoline-1 receptor(I1R) with Ki values of 4.2±3.2 nmol/L, 13.0±4.2 nmol/L.

Moxonidine hydrochloride
B3314-100	ApexBio	100 mg	EUR 864.00
Description: Moxonidine hydrochloride is a mixed agonist of ?2-adrenergic receptor (?2AR) and imidazoline-1 receptor(I1R) with Ki values of 4.2±3.2 nmol/L, 13.0±4.2 nmol/L.

Moxonidine hydrochloride
B3314-50	ApexBio	50 mg	EUR 502.00
Description: Moxonidine hydrochloride is a mixed agonist of ?2-adrenergic receptor (?2AR) and imidazoline-1 receptor(I1R) with Ki values of 4.2±3.2 nmol/L, 13.0±4.2 nmol/L.

Bupropion hydrochloride
B3326-5.1	ApexBio	10 mM (in 1mL DMSO)	EUR 108.00
Description: Bupropion hydrochloride is a dual effective inhibitor of norepinephrine and dopamine neurotransmitter with the IC50 values of 6.5 ± 0.6?M and 3.4 ± 0.4 ?M, respectively [1].

Bupropion hydrochloride
B3326-50	ApexBio	50 mg	EUR 128.00
Description: Bupropion hydrochloride is a dual effective inhibitor of norepinephrine and dopamine neurotransmitter with the IC50 values of 6.5 ± 0.6?M and 3.4 ± 0.4 ?M, respectively [1].

Bupropion hydrochloride
B3326-S	ApexBio	Evaluation Sample	EUR 81.00
Description: Bupropion hydrochloride is a dual effective inhibitor of norepinephrine and dopamine neurotransmitter with the IC50 values of 6.5 ± 0.6?M and 3.4 ± 0.4 ?M, respectively [1].

Sotalol hydrochloride
B3341-100	ApexBio	100 mg	EUR 139.00
Description: Sotalol hydrochloride is a potent and non-selective antagonist of ?-adrenergic receptor. Sotalol is also an inhibitor of potassinm channels with the IC50 value of ~1.2mM in HEK cell lines [1].

Sotalol hydrochloride
B3341-200	ApexBio	200 mg	EUR 187.00
Description: Sotalol hydrochloride is a potent and non-selective antagonist of ?-adrenergic receptor. Sotalol is also an inhibitor of potassinm channels with the IC50 value of ~1.2mM in HEK cell lines [1].

Sotalol hydrochloride
B3341-5.1	ApexBio	10 mM (in 1mL DMSO)	EUR 119.00
Description: Sotalol hydrochloride is a potent and non-selective antagonist of ?-adrenergic receptor. Sotalol is also an inhibitor of potassinm channels with the IC50 value of ~1.2mM in HEK cell lines [1].

Sotalol hydrochloride
B3341-50	ApexBio	50 mg	EUR 106.00
Description: Sotalol hydrochloride is a potent and non-selective antagonist of ?-adrenergic receptor. Sotalol is also an inhibitor of potassinm channels with the IC50 value of ~1.2mM in HEK cell lines [1].

Sotalol hydrochloride
B3341-S	ApexBio	Evaluation Sample	EUR 81.00
Description: Sotalol hydrochloride is a potent and non-selective antagonist of ?-adrenergic receptor. Sotalol is also an inhibitor of potassinm channels with the IC50 value of ~1.2mM in HEK cell lines [1].

Miglustat hydrochloride
B3402-10	ApexBio	10 mg	EUR 312.00
Description: Miglustat Hhydrochloride is an inhibitor of glucosylceramide synthase, primarily to treat Type I Gaucher disease (GD1).

Miglustat hydrochloride
B3402-25	ApexBio	25 mg	EUR 641.00
Description: Miglustat Hhydrochloride is an inhibitor of glucosylceramide synthase, primarily to treat Type I Gaucher disease (GD1).

Miglustat hydrochloride
B3402-5	ApexBio	5 mg	EUR 195.00
Description: Miglustat Hhydrochloride is an inhibitor of glucosylceramide synthase, primarily to treat Type I Gaucher disease (GD1).

Solifenacin hydrochloride
B3415-10	ApexBio	10 mg	EUR 321.00
Description: Solifenacin Hcl(YM905 Hcl; Vesicare Hcl) is a muscarinic receptor antagonist.

Solifenacin hydrochloride
B3415-100	ApexBio	100 mg	EUR 1407.00
Description: Solifenacin Hcl(YM905 Hcl; Vesicare Hcl) is a muscarinic receptor antagonist.

Solifenacin hydrochloride
B3415-5	ApexBio	5 mg	EUR 231.00
Description: Solifenacin Hcl(YM905 Hcl; Vesicare Hcl) is a muscarinic receptor antagonist.

Solifenacin hydrochloride
B3415-5.1	ApexBio	10 mM (in 1mL DMSO)	EUR 248.00
Description: Solifenacin Hcl(YM905 Hcl; Vesicare Hcl) is a muscarinic receptor antagonist.

Solifenacin hydrochloride
B3415-50	ApexBio	50 mg	EUR 864.00
Description: Solifenacin Hcl(YM905 Hcl; Vesicare Hcl) is a muscarinic receptor antagonist.

Vigabatrin Hydrochloride
B3421-10	ApexBio	10 mg	EUR 142.00
Description: Vigabatrin Hcl(?-Vinyl-GABA; Sabril) is a structural analog of the inhibitory neurotransmitter ?-aminobutyric acid (GABA) that irreversibly inhibits the catabolism of GABA by GABA transaminase.

Vigabatrin Hydrochloride
B3421-25	ApexBio	25 mg	EUR 270.00
Description: Vigabatrin Hcl(?-Vinyl-GABA; Sabril) is a structural analog of the inhibitory neurotransmitter ?-aminobutyric acid (GABA) that irreversibly inhibits the catabolism of GABA by GABA transaminase.

Vigabatrin Hydrochloride
B3421-50	ApexBio	50 mg	EUR 440.00
Description: Vigabatrin Hcl(?-Vinyl-GABA; Sabril) is a structural analog of the inhibitory neurotransmitter ?-aminobutyric acid (GABA) that irreversibly inhibits the catabolism of GABA by GABA transaminase.

Flavoxate hydrochloride
B3433-5	ApexBio	5 mg	EUR 131.00
Description: Flavoxate Hydrochloride(DW-61 Hydrochloride) is a muscarinic AChR antagonist used in various urinary syndromes and as an antispasmodic.

Flavoxate hydrochloride
B3433-5.1	ApexBio	10 mM (in 1mL DMSO)	EUR 166.00
Description: Flavoxate Hydrochloride(DW-61 Hydrochloride) is a muscarinic AChR antagonist used in various urinary syndromes and as an antispasmodic.

Flavoxate hydrochloride
B3433-50	ApexBio	50 mg	EUR 363.00
Description: Flavoxate Hydrochloride(DW-61 Hydrochloride) is a muscarinic AChR antagonist used in various urinary syndromes and as an antispasmodic.

Tiagabine hydrochloride
B3443-10	ApexBio	10 mg	EUR 102.00

Tiagabine hydrochloride
B3443-5.1	ApexBio	10 mM (in 1mL DMSO)	EUR 108.00

Lercanidipine hydrochloride
B3482-10	ApexBio	10 mg	EUR 119.00

Lercanidipine hydrochloride
B3482-100	ApexBio	100 mg	EUR 453.00

Lercanidipine hydrochloride
B3482-200	ApexBio	200 mg	EUR 592.00

Lercanidipine hydrochloride
B3482-5.1	ApexBio	10 mM (in 1mL DMSO)	EUR 132.00

Lercanidipine hydrochloride
B3482-50	ApexBio	50 mg	EUR 313.00

Sarpogrelate hydrochloride
B3494-10	ApexBio	10 mg	EUR 139.00
Description: Ki: 8.39 nMSarpogrelate (MCI-9042) was shown to have the same affinity as ritanserin for 5-HT2A receptors, [1].The blockade of 5-HT2A receptors can inhibit thrombus formation suppresses platelet aggregation and inhibits vascular smooth muscle cell proliferation [2].

Sarpogrelate hydrochloride
B3494-100	ApexBio	100 mg	EUR 421.00
Description: Ki: 8.39 nMSarpogrelate (MCI-9042) was shown to have the same affinity as ritanserin for 5-HT2A receptors, [1].The blockade of 5-HT2A receptors can inhibit thrombus formation suppresses platelet aggregation and inhibits vascular smooth muscle cell proliferation [2].

Sarpogrelate hydrochloride
B3494-5.1	ApexBio	10 mM (in 1mL DMSO)	EUR 150.00
Description: Ki: 8.39 nMSarpogrelate (MCI-9042) was shown to have the same affinity as ritanserin for 5-HT2A receptors, [1].The blockade of 5-HT2A receptors can inhibit thrombus formation suppresses platelet aggregation and inhibits vascular smooth muscle cell proliferation [2].

Sarpogrelate hydrochloride
B3494-50	ApexBio	50 mg	EUR 322.00
Description: Ki: 8.39 nMSarpogrelate (MCI-9042) was shown to have the same affinity as ritanserin for 5-HT2A receptors, [1].The blockade of 5-HT2A receptors can inhibit thrombus formation suppresses platelet aggregation and inhibits vascular smooth muscle cell proliferation [2].

Ramosetron Hydrochloride
B3536-10	ApexBio	10 mg	EUR 126.00

Ramosetron Hydrochloride
B3536-100	ApexBio	100 mg	EUR 661.00