Cell culture-derived influenza vaccines in the severe 2017-2018 epidemic season: a step towards improved influenza vaccine effectiveness.

The 2017-2018 seasonal influenza epidemics are severe in the US and Australia where A (H3N2) virus subtype dominated. Although circulating A (H3N2) virus antigen is not different from that recommended by the WHO for vaccine production, the overall interim estimate of vaccine effectiveness was under the historical average (33%) for A (H3N2) virus. The majority (USA) or all (Australia) dose of vaccine contains several amino acid changes in the hemagglutinin protein, which is produced from the necessary adaptation of the virus to embryonated chicken eggs used to manufacture the vaccine most. Previous reports have suggested the potential negative impact of the substitution of egg-driven performance of the vaccine. With the support of Barda, two vaccines licensed in the US is produced in cell culture: a recombinant influenza vaccine (RIV, Flublok ™) produced in insect cells and inactivated vaccines adult mammalian cells (ccIIV, Flucelvax ™). CcIIV quadrivalent (ccIIV4) vaccine for the 2017-2018 influenza season was produced using seed virus A (H3N2) distributed exclusively in cell culture and therefore less adaptative changes eggs. ccIIV dose fairly distributed (but not RIV dose) to allow the initial estimates of higher efficacy relative to traditional egg-based vaccine, the study details pending. The increased availability of certain product comparison vaccine effectiveness estimates for cell-based vaccine and egg-based can provide important clues to inform vaccine product improvements moving forward.

Diclofenac Diethylamine

B1928-50 50 mg
EUR 153.6
Description: Diclofenac diethylamine is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.

Diclofenac Diethylamine

B1928-S Evaluation Sample
EUR 97.2
Description: Diclofenac diethylamine is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.

Diclofenac (diethylamine)

HY-15036A 10mM/1mL
EUR 135.6

Tetracycline, Hydrochloride

CH054 25 g
EUR 142.8

Tetracycline, Hydrochloride

CH055 100 g
EUR 204

Ciprofloxacin hydrochloride

C032-25G 25 g
EUR 199.2

Ciprofloxacin hydrochloride

C032-5G 5 g
EUR 74.4

Clindamycin Hydrochloride

C035-100MG 100 mg
EUR 243.6

Clindamycin Hydrochloride

C035-50MG 50 mg
EUR 152.4

Chlortetracycline Hydrochloride

C072-100G 100 g
EUR 376.8

Chlortetracycline Hydrochloride

C072-25G 25 g
EUR 157.2

Chlortetracycline Hydrochloride

C072-5G 5 g
EUR 78

Cefozopran Hydrochloride

C099-100MG 100 mg
EUR 300

Cysteamine hydrochloride

C212-25G 25 g
EUR 78

Cysteamine hydrochloride

C212-4x25G 4 x 25 g
EUR 154.8

Ceftiofur Hydrochloride

C228-1G 1 g
EUR 129.6

Ceftiofur Hydrochloride

C228-5G 5 g
EUR 387.6

Cefmenoxime Hydrochloride

C240-100MG 100mg
EUR 136.8

Cefmenoxime Hydrochloride

C240-500MG 500mg
EUR 334.8

Cinacalcet Hydrochloride

C242-100MG 100mg
EUR 513.6

Cinacalcet Hydrochloride

C242-10MG 10mg
EUR 94.8

Enrofloxacin hydrochloride

E007-100MG 100 mg
EUR 147.6

Enrofloxacin hydrochloride

E007-1G 1 g
EUR 776.4

Enrofloxacin hydrochloride

E007-500MG 500 mg
EUR 475.2

Erlotinib hydrochloride

E017-100MG 100 mg
EUR 136.8

Erlotinib hydrochloride

E017-1G 1 g
EUR 373.2

Pazopanib Hydrochloride

A8347-100 100 mg
EUR 268.8
Description: Pazopanib HCl is a receptor tyrosine kinase inhibitor that targets multiple kinases, including VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit, and c-Fms, with IC50s 10nM, 30nM, 47nM, 84nM, 74nM, 140nM, and 146nM respectively [1-3].

Pazopanib Hydrochloride

A8347-25 25 mg
EUR 129.6
Description: Pazopanib HCl is a receptor tyrosine kinase inhibitor that targets multiple kinases, including VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit, and c-Fms, with IC50s 10nM, 30nM, 47nM, 84nM, 74nM, 140nM, and 146nM respectively [1-3].

Pazopanib Hydrochloride

A8347-5.1 10 mM (in 1mL DMSO)
EUR 135.6
Description: Pazopanib HCl is a receptor tyrosine kinase inhibitor that targets multiple kinases, including VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit, and c-Fms, with IC50s 10nM, 30nM, 47nM, 84nM, 74nM, 140nM, and 146nM respectively [1-3].

Pazopanib Hydrochloride

A8347-500 500 mg
EUR 727.2
Description: Pazopanib HCl is a receptor tyrosine kinase inhibitor that targets multiple kinases, including VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit, and c-Fms, with IC50s 10nM, 30nM, 47nM, 84nM, 74nM, 140nM, and 146nM respectively [1-3].

Pazopanib Hydrochloride

A8347-S Evaluation Sample
EUR 97.2
Description: Pazopanib HCl is a receptor tyrosine kinase inhibitor that targets multiple kinases, including VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit, and c-Fms, with IC50s 10nM, 30nM, 47nM, 84nM, 74nM, 140nM, and 146nM respectively [1-3].

Bestatin hydrochloride

A8621-10 10 mg
EUR 157.2
Description: Bestatin hydrochloride, also known as Ubenimex, is an inhibitor of aminopeptidase B and N (APN)/CD13 [1].Bestatin, an antibiotic of microbial origin, is a potent inhibitor of some aminopeptidases which can be administered to cultured cells, intact animals and humans with low toxicity.

Bestatin hydrochloride

A8621-100 100 mg
EUR 532.8
Description: Bestatin hydrochloride, also known as Ubenimex, is an inhibitor of aminopeptidase B and N (APN)/CD13 [1].Bestatin, an antibiotic of microbial origin, is a potent inhibitor of some aminopeptidases which can be administered to cultured cells, intact animals and humans with low toxicity.

Bestatin hydrochloride

A8621-25 25 mg
EUR 226.8
Description: Bestatin hydrochloride, also known as Ubenimex, is an inhibitor of aminopeptidase B and N (APN)/CD13 [1].Bestatin, an antibiotic of microbial origin, is a potent inhibitor of some aminopeptidases which can be administered to cultured cells, intact animals and humans with low toxicity.

Bestatin hydrochloride

A8621-5 5 mg
EUR 129.6
Description: Bestatin hydrochloride, also known as Ubenimex, is an inhibitor of aminopeptidase B and N (APN)/CD13 [1].Bestatin, an antibiotic of microbial origin, is a potent inhibitor of some aminopeptidases which can be administered to cultured cells, intact animals and humans with low toxicity.

Flavopiridol hydrochloride

A8640-10 10 mg
EUR 129.6
Description: Flavopiridol hydrochloride is a selective inhibitor of CDK1, CDK2, CDK4 and CDK6 with IC50 value all ~41 nM as well as CDK7 with 300nM [1] [2] [3].CDKs are protein kinase families which involve in the process of regulating transcription, mRNA processing, cell differentiation and cell cycle.

Flavopiridol hydrochloride

A8640-100 100 mg
EUR 528
Description: Flavopiridol hydrochloride is a selective inhibitor of CDK1, CDK2, CDK4 and CDK6 with IC50 value all ~41 nM as well as CDK7 with 300nM [1] [2] [3].CDKs are protein kinase families which involve in the process of regulating transcription, mRNA processing, cell differentiation and cell cycle.

Flavopiridol hydrochloride

A8640-1000 1 g
EUR 3259.2
Description: Flavopiridol hydrochloride is a selective inhibitor of CDK1, CDK2, CDK4 and CDK6 with IC50 value all ~41 nM as well as CDK7 with 300nM [1] [2] [3].CDKs are protein kinase families which involve in the process of regulating transcription, mRNA processing, cell differentiation and cell cycle.

Flavopiridol hydrochloride

A8640-25 25 mg
EUR 199.2
Description: Flavopiridol hydrochloride is a selective inhibitor of CDK1, CDK2, CDK4 and CDK6 with IC50 value all ~41 nM as well as CDK7 with 300nM [1] [2] [3].CDKs are protein kinase families which involve in the process of regulating transcription, mRNA processing, cell differentiation and cell cycle.

Flavopiridol hydrochloride

A8640-5.1 10 mM (in 1mL DMSO)
EUR 129.6
Description: Flavopiridol hydrochloride is a selective inhibitor of CDK1, CDK2, CDK4 and CDK6 with IC50 value all ~41 nM as well as CDK7 with 300nM [1] [2] [3].CDKs are protein kinase families which involve in the process of regulating transcription, mRNA processing, cell differentiation and cell cycle.

Regorafenib hydrochloride

A3750-10 10 mg
EUR 150
Description: Regorafenib (BAY 73-4506) is a multikinase inhibitor with IC50 of 17, 40 and 69 nM c-KIT, VEGFR2, B-Raf.

Regorafenib hydrochloride

A3750-100 100 mg
EUR 282
Description: Regorafenib (BAY 73-4506) is a multikinase inhibitor with IC50 of 17, 40 and 69 nM c-KIT, VEGFR2, B-Raf.

Regorafenib hydrochloride

A3750-200 200 mg
EUR 582
Description: Regorafenib (BAY 73-4506) is a multikinase inhibitor with IC50 of 17, 40 and 69 nM c-KIT, VEGFR2, B-Raf.

Regorafenib hydrochloride

A3750-5.1 10 mM (in 1mL DMSO)
EUR 199.2
Description: Regorafenib (BAY 73-4506) is a multikinase inhibitor with IC50 of 17, 40 and 69 nM c-KIT, VEGFR2, B-Raf.

Regorafenib hydrochloride

A3750-50 50 mg
EUR 199.2
Description: Regorafenib (BAY 73-4506) is a multikinase inhibitor with IC50 of 17, 40 and 69 nM c-KIT, VEGFR2, B-Raf.

Resminostat hydrochloride

A3755-10 10 mg
EUR 428.4
Description: Resminostat is an inhibitor of histone deacetylase (HDAC) with IC50 values of 42.5nM, 50.1nM and 71.8nM, respectively against HDAC1, 3 and 6 [1].

Resminostat hydrochloride

A3755-100 100 mg
EUR 1905.6
Description: Resminostat is an inhibitor of histone deacetylase (HDAC) with IC50 values of 42.5nM, 50.1nM and 71.8nM, respectively against HDAC1, 3 and 6 [1].

Resminostat hydrochloride

A3755-5.1 10 mM (in 1mL DMSO)
EUR 464.4
Description: Resminostat is an inhibitor of histone deacetylase (HDAC) with IC50 values of 42.5nM, 50.1nM and 71.8nM, respectively against HDAC1, 3 and 6 [1].

Resminostat hydrochloride

A3755-50 50 mg
EUR 1209.6
Description: Resminostat is an inhibitor of histone deacetylase (HDAC) with IC50 values of 42.5nM, 50.1nM and 71.8nM, respectively against HDAC1, 3 and 6 [1].

Rimonabant hydrochloride

A3766-10 10 mg
EUR 186
Description: Rimonabant, also known as SR141716, was the first selective central cannabinoid (CB1) receptor inverse agonist (Ki = 1.8 nM) to be developed as an appetite suppressant, anti-obesity drug.

Rimonabant hydrochloride

A3766-100 100 mg
EUR 710.4
Description: Rimonabant, also known as SR141716, was the first selective central cannabinoid (CB1) receptor inverse agonist (Ki = 1.8 nM) to be developed as an appetite suppressant, anti-obesity drug.

Rimonabant hydrochloride

A3766-5.1 10 mM (in 1mL DMSO)
EUR 199.2
Description: Rimonabant, also known as SR141716, was the first selective central cannabinoid (CB1) receptor inverse agonist (Ki = 1.8 nM) to be developed as an appetite suppressant, anti-obesity drug.

Rimonabant hydrochloride

A3766-50 50 mg
EUR 494.4
Description: Rimonabant, also known as SR141716, was the first selective central cannabinoid (CB1) receptor inverse agonist (Ki = 1.8 nM) to be developed as an appetite suppressant, anti-obesity drug.

Rotigotine hydrochloride

A3777-100 100 mg
EUR 480
Description: Rotigotine is dopamine D2 and D3 receptor agonist. Ki values are 13 and 0.71 nM for D2 and D3 respectively. Rotigotine also has significant affinity for 5-HT1A and adrenergic ?2B receptors. Rotigotine exhibits antiparkinsonian acitivity.

Rotigotine hydrochloride

A3777-200 200 mg
EUR 812.4
Description: Rotigotine is dopamine D2 and D3 receptor agonist. Ki values are 13 and 0.71 nM for D2 and D3 respectively. Rotigotine also has significant affinity for 5-HT1A and adrenergic ?2B receptors. Rotigotine exhibits antiparkinsonian acitivity.

Rotigotine hydrochloride

A3777-5.1 10 mM (in 1mL DMSO)
EUR 417.6
Description: Rotigotine is dopamine D2 and D3 receptor agonist. Ki values are 13 and 0.71 nM for D2 and D3 respectively. Rotigotine also has significant affinity for 5-HT1A and adrenergic ?2B receptors. Rotigotine exhibits antiparkinsonian acitivity.

Rotigotine hydrochloride

A3777-50 50 mg
EUR 360
Description: Rotigotine is dopamine D2 and D3 receptor agonist. Ki values are 13 and 0.71 nM for D2 and D3 respectively. Rotigotine also has significant affinity for 5-HT1A and adrenergic ?2B receptors. Rotigotine exhibits antiparkinsonian acitivity.

Rotigotine hydrochloride

A3777-500 500 mg
EUR 1663.2
Description: Rotigotine is dopamine D2 and D3 receptor agonist. Ki values are 13 and 0.71 nM for D2 and D3 respectively. Rotigotine also has significant affinity for 5-HT1A and adrenergic ?2B receptors. Rotigotine exhibits antiparkinsonian acitivity.

Tipiracil hydrochloride

A3875-10 10 mg
EUR 553.2
Description: Tipiracil is an inhibitor of Thymidine phosphorylase (TP). Thymidine phosphorylase (TP)is a key enzyme in the pyrimidine nucleoside salvage pathway.

Tipiracil hydrochloride

A3875-25 25 mg
EUR 774
Description: Tipiracil is an inhibitor of Thymidine phosphorylase (TP). Thymidine phosphorylase (TP)is a key enzyme in the pyrimidine nucleoside salvage pathway.

Tipiracil hydrochloride

A3875-5 5 mg
EUR 382.8
Description: Tipiracil is an inhibitor of Thymidine phosphorylase (TP). Thymidine phosphorylase (TP)is a key enzyme in the pyrimidine nucleoside salvage pathway.

Tipiracil hydrochloride

A3875-5.1 10 mM (in 1mL DMSO)
EUR 351.6
Description: Tipiracil is an inhibitor of Thymidine phosphorylase (TP). Thymidine phosphorylase (TP)is a key enzyme in the pyrimidine nucleoside salvage pathway.

Tipiracil hydrochloride

A3875-50 50 mg
EUR 1230
Description: Tipiracil is an inhibitor of Thymidine phosphorylase (TP). Thymidine phosphorylase (TP)is a key enzyme in the pyrimidine nucleoside salvage pathway.

Vandetanib hydrochloride

A3906-100 100 mg
EUR 517.2
Description: Description: IC50 Value: 40 nM (VEGFR2) [1]; 500 nM (EGFR) [2] Vandetanib is an anti-cancer drug that is used for the treatment of certain tumours of thethyroid gland.

Vandetanib hydrochloride

A3906-25 25 mg
EUR 201.6
Description: Description: IC50 Value: 40 nM (VEGFR2) [1]; 500 nM (EGFR) [2] Vandetanib is an anti-cancer drug that is used for the treatment of certain tumours of thethyroid gland.

Vernakalant Hydrochloride

A3915-10 10 mg
EUR 847.2
Description: IC50: Vernakalant inhibits two specific potassium currents, IKur (IC50 = 9 ??) and IKACh (IC50=10 ?M) which are only present in atrial myocardium [1].Vernakalant blocks atrial potassium channels, thereby prolonging repolarization.

Vernakalant Hydrochloride

A3915-100 100 mg
EUR 3316.8
Description: IC50: Vernakalant inhibits two specific potassium currents, IKur (IC50 = 9 ??) and IKACh (IC50=10 ?M) which are only present in atrial myocardium [1].Vernakalant blocks atrial potassium channels, thereby prolonging repolarization.

Vernakalant Hydrochloride

A3915-50 50 mg
EUR 2090.4
Description: IC50: Vernakalant inhibits two specific potassium currents, IKur (IC50 = 9 ??) and IKACh (IC50=10 ?M) which are only present in atrial myocardium [1].Vernakalant blocks atrial potassium channels, thereby prolonging repolarization.

Vilazodone Hydrochloride

A3919-10 10 mg
EUR 129.6
Description: Vilazodone (EMD 68843; SB 659746A; 5-{4-[4-(5-cyano-3-indolyl)-butyl]-1-piperazinyl}-benzofuran-2-carboxamide hydrochloride) is a combined serotonin specific reuptake inhibitor (SSRI) and 5-HT1A receptor partial agonist currently under clinical evaluation for the treatment of major depression.

Vilazodone Hydrochloride

A3919-5.1 10 mM (in 1mL DMSO)
EUR 129.6
Description: Vilazodone (EMD 68843; SB 659746A; 5-{4-[4-(5-cyano-3-indolyl)-butyl]-1-piperazinyl}-benzofuran-2-carboxamide hydrochloride) is a combined serotonin specific reuptake inhibitor (SSRI) and 5-HT1A receptor partial agonist currently under clinical evaluation for the treatment of major depression.

Vilazodone Hydrochloride

A3919-50 50 mg
EUR 157.2
Description: Vilazodone (EMD 68843; SB 659746A; 5-{4-[4-(5-cyano-3-indolyl)-butyl]-1-piperazinyl}-benzofuran-2-carboxamide hydrochloride) is a combined serotonin specific reuptake inhibitor (SSRI) and 5-HT1A receptor partial agonist currently under clinical evaluation for the treatment of major depression.

Voreloxin Hydrochloride

A3925-10 10 mg
EUR 895.2
Description: Voreloxin is a small molecule and a naphthyridine analogue with antineoplastic activity. Vosaroxin intercalates into DNA in a site-specific manner and blocks the re-ligation process carried out by topoisomerase II during DNA replication.

Voreloxin Hydrochloride

A3925-5 5 mg
EUR 656.4
Description: Voreloxin is a small molecule and a naphthyridine analogue with antineoplastic activity. Vosaroxin intercalates into DNA in a site-specific manner and blocks the re-ligation process carried out by topoisomerase II during DNA replication.

Voreloxin Hydrochloride

A3925-5.1 10 mM (in 1mL DMSO)
EUR 717.6
Description: Voreloxin is a small molecule and a naphthyridine analogue with antineoplastic activity. Vosaroxin intercalates into DNA in a site-specific manner and blocks the re-ligation process carried out by topoisomerase II during DNA replication.

PJ34 hydrochloride

A4159-10 10 mg
EUR 142.8
Description: PJ34 is a novel and potent inhibitor of poly(ADP-ribose) polymerase (PARP), an enzyme involved in DNA repair and cell proliferation, that dose-dependently inhibits purified PARP enzyme in a cell-free assay with half maximal effective concentration EC50 value of 20 nM.

PJ34 hydrochloride

A4159-5 5 mg
EUR 129.6
Description: PJ34 is a novel and potent inhibitor of poly(ADP-ribose) polymerase (PARP), an enzyme involved in DNA repair and cell proliferation, that dose-dependently inhibits purified PARP enzyme in a cell-free assay with half maximal effective concentration EC50 value of 20 nM.

PJ34 hydrochloride

A4159-5.1 10 mM (in 1mL DMSO)
EUR 150
Description: PJ34 is a novel and potent inhibitor of poly(ADP-ribose) polymerase (PARP), an enzyme involved in DNA repair and cell proliferation, that dose-dependently inhibits purified PARP enzyme in a cell-free assay with half maximal effective concentration EC50 value of 20 nM.

PJ34 hydrochloride

A4159-50 50 mg
EUR 296.4
Description: PJ34 is a novel and potent inhibitor of poly(ADP-ribose) polymerase (PARP), an enzyme involved in DNA repair and cell proliferation, that dose-dependently inhibits purified PARP enzyme in a cell-free assay with half maximal effective concentration EC50 value of 20 nM.

PJ34 hydrochloride

A4159-S Evaluation Sample
EUR 97.2
Description: PJ34 is a novel and potent inhibitor of poly(ADP-ribose) polymerase (PARP), an enzyme involved in DNA repair and cell proliferation, that dose-dependently inhibits purified PARP enzyme in a cell-free assay with half maximal effective concentration EC50 value of 20 nM.

Dimethylamine hydrochloride

DB0410 500g
EUR 116.38

Daunorubicin hydrochloride

D001-10MG 10 mg
EUR 142.8

Daunorubicin hydrochloride

D001-50MG 50 mg
EUR 480

Difloxacin hydrochloride

D021-1G 1 g
EUR 133.2

Difloxacin hydrochloride

D021-5G 5 g
EUR 438

Demeclocycline hydrochloride

D032-1G 1 g
EUR 208.8

Demeclocycline hydrochloride

D032-250MG 250 mg
EUR 105.6

Demeclocycline hydrochloride

D032-5G 5 g
EUR 646.8

Doxycycline Hydrochloride

D065-25MG 25mg
EUR 410.4

Doxycycline Hydrochloride

D065-5MG 5mg
EUR 142.8

Dalbavancin Hydrochloride

D092-10MG 10mg
EUR 152.4

Dalbavancin Hydrochloride

D092-50MG 50mg
EUR 456

Cefepime Hydrochloride

C009-100MG 100 mg
EUR 320.4

Ceftazidime Hydrochloride

C020-1G 1 g
EUR 746.4

Niguldipine (hydrochloride)

C3067-10 10 mg
EUR 164.4
Description: Ki = 0.16 nM: ?1A-adrenoceptor antagonistIC50s = 0.4 ?M: inhibits L-type Ca2+ channelsIC50s = 0.9 ?M: suppresses T-type Ca2+ channelsNiguldipine is a less potent Ca2+ channel blocker and potent, selective ?1A-adrenoceptor receptor antagonist.

Niguldipine (hydrochloride)

C3067-25 25 mg
EUR 308.4
Description: Ki = 0.16 nM: ?1A-adrenoceptor antagonistIC50s = 0.4 ?M: inhibits L-type Ca2+ channelsIC50s = 0.9 ?M: suppresses T-type Ca2+ channelsNiguldipine is a less potent Ca2+ channel blocker and potent, selective ?1A-adrenoceptor receptor antagonist.

AD57 (hydrochloride)

C3080-1 1 mg
EUR 141.6
Description: IC50: 2 nM: blocks the receptor tyrosine kinase RET in Drosophila.AD57, as a polypharmacological cancer therapeutic, is designed to regulate multiple targets related to cancer.

AD57 (hydrochloride)

C3080-10 10 mg
EUR 714
Description: IC50: 2 nM: blocks the receptor tyrosine kinase RET in Drosophila.AD57, as a polypharmacological cancer therapeutic, is designed to regulate multiple targets related to cancer.

AD57 (hydrochloride)

C3080-5 5 mg
EUR 428.4
Description: IC50: 2 nM: blocks the receptor tyrosine kinase RET in Drosophila.AD57, as a polypharmacological cancer therapeutic, is designed to regulate multiple targets related to cancer.

Pargyline (hydrochloride)

C3106-1000 1 g
EUR 139.2
Description: IC50: 11.52 nM: inhibits monoamine oxidase (MAO) type A (MAO-A).IC50: 8.2 nM: blocks MAO type B (MAO-B).Pargyline, an irreversible and non-selective inhibitor of MAO, is used to treat moderate hypertension and cancer cells.

Pargyline (hydrochloride)

C3106-5000 5 g
EUR 410.4
Description: IC50: 11.52 nM: inhibits monoamine oxidase (MAO) type A (MAO-A).IC50: 8.2 nM: blocks MAO type B (MAO-B).Pargyline, an irreversible and non-selective inhibitor of MAO, is used to treat moderate hypertension and cancer cells.

Clenbuterol (hydrochloride)

C3119-100 100 mg
EUR 258
Description: Clenbuterol is a sympathomimetic ?2-adrenoceptor agonist. ?2-adrenoceptor agonists, mainly long-acting ?2-adrenoceptor agonists, are an important pharmacological approach to induce bronchodilation in patients with chronic obstructive pulmonary disease.

Clenbuterol (hydrochloride)

C3119-25 25 mg
EUR 130.8
Description: Clenbuterol is a sympathomimetic ?2-adrenoceptor agonist. ?2-adrenoceptor agonists, mainly long-acting ?2-adrenoceptor agonists, are an important pharmacological approach to induce bronchodilation in patients with chronic obstructive pulmonary disease.

Clenbuterol (hydrochloride)

C3119-5.1 10 mM (in 1mL DMSO)
EUR 135.6
Description: Clenbuterol is a sympathomimetic ?2-adrenoceptor agonist. ?2-adrenoceptor agonists, mainly long-acting ?2-adrenoceptor agonists, are an important pharmacological approach to induce bronchodilation in patients with chronic obstructive pulmonary disease.

Clenbuterol (hydrochloride)

C3119-50 50 mg
EUR 189.6
Description: Clenbuterol is a sympathomimetic ?2-adrenoceptor agonist. ?2-adrenoceptor agonists, mainly long-acting ?2-adrenoceptor agonists, are an important pharmacological approach to induce bronchodilation in patients with chronic obstructive pulmonary disease.

CBL0137 (hydrochloride)

C3192-10 10 mg
EUR 529.2
Description: EC50: 0.37 ?M for activating p53; 0.47 ?M for inhibiting NF-?B CBL0137 (hydrochloride) is a curaxin that activates p53 and inhibits NF-?B.

CBL0137 (hydrochloride)

C3192-25 25 mg
EUR 1071.6
Description: EC50: 0.37 ?M for activating p53; 0.47 ?M for inhibiting NF-?B CBL0137 (hydrochloride) is a curaxin that activates p53 and inhibits NF-?B.

CBL0137 (hydrochloride)

C3192-5 5 mg
EUR 331.2
Description: EC50: 0.37 ?M for activating p53; 0.47 ?M for inhibiting NF-?B CBL0137 (hydrochloride) is a curaxin that activates p53 and inhibits NF-?B.

CBL0137 (hydrochloride)

C3192-5.1 10 mM (in 1mL DMSO)
EUR 282
Description: EC50: 0.37 ?M for activating p53; 0.47 ?M for inhibiting NF-?B CBL0137 (hydrochloride) is a curaxin that activates p53 and inhibits NF-?B.

CBL0137 (hydrochloride)

C3192-50 50 mg
EUR 1851.6
Description: EC50: 0.37 ?M for activating p53; 0.47 ?M for inhibiting NF-?B CBL0137 (hydrochloride) is a curaxin that activates p53 and inhibits NF-?B.

CPTH2 (hydrochloride)

C3208-10 10 mg
EUR 231.6
Description: CPTH2 is an inhibitor of HAT activity of Gcn5.

CPTH2 (hydrochloride)

C3208-5 5 mg
EUR 192
Description: CPTH2 is an inhibitor of HAT activity of Gcn5.

Clinafloxacin (hydrochloride)

C3345-100 100 mg
EUR 184.8
Description: Clinafloxacin is a broad-spectrum antibiotic of the quinolone carboxylic acid category that inhibits both DNA gyrase and topoisomerase IV dually in Streptococcus pneumonia. Clinafloxacin, a fluoroquinolone, is currently in development for oral and intravenous therapy of serious infections.

Clinafloxacin (hydrochloride)

C3345-1000 1 g
EUR 686.4
Description: Clinafloxacin is a broad-spectrum antibiotic of the quinolone carboxylic acid category that inhibits both DNA gyrase and topoisomerase IV dually in Streptococcus pneumonia. Clinafloxacin, a fluoroquinolone, is currently in development for oral and intravenous therapy of serious infections.

Clinafloxacin (hydrochloride)

C3345-250 250 mg
EUR 309.6
Description: Clinafloxacin is a broad-spectrum antibiotic of the quinolone carboxylic acid category that inhibits both DNA gyrase and topoisomerase IV dually in Streptococcus pneumonia. Clinafloxacin, a fluoroquinolone, is currently in development for oral and intravenous therapy of serious infections.

Clinafloxacin (hydrochloride)

C3345-500 500 mg
EUR 459.6
Description: Clinafloxacin is a broad-spectrum antibiotic of the quinolone carboxylic acid category that inhibits both DNA gyrase and topoisomerase IV dually in Streptococcus pneumonia. Clinafloxacin, a fluoroquinolone, is currently in development for oral and intravenous therapy of serious infections.

Isoxsuprine (hydrochloride)

C3347-10000 10 g
EUR 145.2
Description: Isoxsuprine is a modulator of ?2 adrenoreceptor and has agonist or antagonist effects.The ?2 adrenoceptors are a class of G protein-coupled receptors that are targets for epinephrine.

Isoxsuprine (hydrochloride)

C3347-5.1 10 mM (in 1mL DMSO)
EUR 135.6
Description: Isoxsuprine is a modulator of ?2 adrenoreceptor and has agonist or antagonist effects.The ?2 adrenoceptors are a class of G protein-coupled receptors that are targets for epinephrine.

DAPI (hydrochloride)

C3362-10 10 mg
EUR 146.4

DAPI (hydrochloride)

C3362-25 25 mg
EUR 240

DAPI (hydrochloride)

C3362-5 5 mg
EUR 111.6

Kanosamine (hydrochloride)

C3461-10 10 mg
EUR 528
Description: Kanosamine is the antibiotic produced by Bacillus cereus UW85. Kanosamine showed highly inhibitory effects to the growth of plant-pathogenic oomycetes and moderately inhibitory effects to certain fungi and inhibited few bacterial species tested.

Kanosamine (hydrochloride)

C3461-25 25 mg
EUR 1089.6
Description: Kanosamine is the antibiotic produced by Bacillus cereus UW85. Kanosamine showed highly inhibitory effects to the growth of plant-pathogenic oomycetes and moderately inhibitory effects to certain fungi and inhibited few bacterial species tested.

Kanosamine (hydrochloride)

C3461-5 5 mg
EUR 324
Description: Kanosamine is the antibiotic produced by Bacillus cereus UW85. Kanosamine showed highly inhibitory effects to the growth of plant-pathogenic oomycetes and moderately inhibitory effects to certain fungi and inhibited few bacterial species tested.

Zoniporide (hydrochloride)

C3480-10 10 mg
EUR 278.4
Description: Zoniporide (hydrochloride) is a novel, potent, and selective sodium-hydrogen exchanger isoform-1 (NHE-1) inhibitor [1]. The Na+/H+ exchanger (NHE) has been involved in intracellular pH homeostasis of many mammalian cell types.

Zoniporide (hydrochloride)

C3480-5 5 mg
EUR 181.2
Description: Zoniporide (hydrochloride) is a novel, potent, and selective sodium-hydrogen exchanger isoform-1 (NHE-1) inhibitor [1]. The Na+/H+ exchanger (NHE) has been involved in intracellular pH homeostasis of many mammalian cell types.

Zoniporide (hydrochloride)

C3480-50 50 mg
EUR 1004.4
Description: Zoniporide (hydrochloride) is a novel, potent, and selective sodium-hydrogen exchanger isoform-1 (NHE-1) inhibitor [1]. The Na+/H+ exchanger (NHE) has been involved in intracellular pH homeostasis of many mammalian cell types.

MS023 (hydrochloride)

C3503-1 1 mg
EUR 134.4
Description: IC50: 20, 119, 83, 8, and 8 nM for PRMT1, 3, 4, 6, and 8, respectivelyMS023 is a type I PRMT inhibitor. Protein arginine methyltransferases (PRMTs) play a critical role in various biological processes.

MS023 (hydrochloride)

C3503-10 10 mg
EUR 661.2
Description: IC50: 20, 119, 83, 8, and 8 nM for PRMT1, 3, 4, 6, and 8, respectivelyMS023 is a type I PRMT inhibitor. Protein arginine methyltransferases (PRMTs) play a critical role in various biological processes.

MS023 (hydrochloride)

C3503-25 25 mg
EUR 1375.2
Description: IC50: 20, 119, 83, 8, and 8 nM for PRMT1, 3, 4, 6, and 8, respectivelyMS023 is a type I PRMT inhibitor. Protein arginine methyltransferases (PRMTs) play a critical role in various biological processes.

MS023 (hydrochloride)

C3503-5 5 mg
EUR 398.4
Description: IC50: 20, 119, 83, 8, and 8 nM for PRMT1, 3, 4, 6, and 8, respectivelyMS023 is a type I PRMT inhibitor. Protein arginine methyltransferases (PRMTs) play a critical role in various biological processes.

Chlorprothixene (hydrochloride)

C3509-1000 1 g
EUR 103.2
Description: Chlorprothixene (hydrochloride) is an antagonist of dopamine receptor and histamine receptors [1]. Chlorprothixene is also an inhibitor of GABAA receptor [2]. All of these three receptors are implicated in many neurological processes, including motivation, pleasure, cognition, memory and learning.

Chlorprothixene (hydrochloride)

C3509-10000 10 g
EUR 397.2
Description: Chlorprothixene (hydrochloride) is an antagonist of dopamine receptor and histamine receptors [1]. Chlorprothixene is also an inhibitor of GABAA receptor [2]. All of these three receptors are implicated in many neurological processes, including motivation, pleasure, cognition, memory and learning.

Chlorprothixene (hydrochloride)

C3509-25000 25 g
EUR 796.8
Description: Chlorprothixene (hydrochloride) is an antagonist of dopamine receptor and histamine receptors [1]. Chlorprothixene is also an inhibitor of GABAA receptor [2]. All of these three receptors are implicated in many neurological processes, including motivation, pleasure, cognition, memory and learning.

Chlorprothixene (hydrochloride)

C3509-5.1 10 mM (in 1mL DMSO)
EUR 135.6
Description: Chlorprothixene (hydrochloride) is an antagonist of dopamine receptor and histamine receptors [1]. Chlorprothixene is also an inhibitor of GABAA receptor [2]. All of these three receptors are implicated in many neurological processes, including motivation, pleasure, cognition, memory and learning.

Chlorprothixene (hydrochloride)

C3509-5000 5 g
EUR 249.6
Description: Chlorprothixene (hydrochloride) is an antagonist of dopamine receptor and histamine receptors [1]. Chlorprothixene is also an inhibitor of GABAA receptor [2]. All of these three receptors are implicated in many neurological processes, including motivation, pleasure, cognition, memory and learning.

Cycloguanil (hydrochloride)

C5763-10 10 mg
EUR 130.8
Description: Cycloguanil is an inhibitor of dihydrofolate reductase (DHFR)[1].Dihydrofolate reductase (DHFR) is an enzyme that involved in reducing dihydrofolic acid to tetrahydrofolic acid.

Cycloguanil (hydrochloride)

C5763-25 25 mg
EUR 195.6
Description: Cycloguanil is an inhibitor of dihydrofolate reductase (DHFR)[1].Dihydrofolate reductase (DHFR) is an enzyme that involved in reducing dihydrofolic acid to tetrahydrofolic acid.

Cycloguanil (hydrochloride)

C5763-50 50 mg
EUR 247.2
Description: Cycloguanil is an inhibitor of dihydrofolate reductase (DHFR)[1].Dihydrofolate reductase (DHFR) is an enzyme that involved in reducing dihydrofolic acid to tetrahydrofolic acid.

Bufuralol (hydrochloride)

C5043-1 1 mg
EUR 166.8
Description: Bufuralol is a non-specific ?-adrenergic blocker. Beta adrenergic agonists are medications relaxing muscles of the airways, which widens the airways and leads to easier breathing.

Bufuralol (hydrochloride)

C5043-10 10 mg
EUR 753.6
Description: Bufuralol is a non-specific ?-adrenergic blocker. Beta adrenergic agonists are medications relaxing muscles of the airways, which widens the airways and leads to easier breathing.

Bufuralol (hydrochloride)

C5043-5 5 mg
EUR 548.4
Description: Bufuralol is a non-specific ?-adrenergic blocker. Beta adrenergic agonists are medications relaxing muscles of the airways, which widens the airways and leads to easier breathing.

AN3365 (hydrochloride)

C5068-10 10 mg
EUR 393.6
Description: AN3365 is a potent and selective leucyl-tRNA synthetase inhibitor [1].The leucyl-tRNA synthetase belongs to a member of the class I aminoacyl-tRNA synthetase family.

AN3365 (hydrochloride)

C5068-25 25 mg
EUR 790.8
Description: AN3365 is a potent and selective leucyl-tRNA synthetase inhibitor [1].The leucyl-tRNA synthetase belongs to a member of the class I aminoacyl-tRNA synthetase family.

AN3365 (hydrochloride)

C5068-5 5 mg
EUR 247.2
Description: AN3365 is a potent and selective leucyl-tRNA synthetase inhibitor [1].The leucyl-tRNA synthetase belongs to a member of the class I aminoacyl-tRNA synthetase family.

Calindol (hydrochloride)

C5329-10 10 mg
EUR 528
Description: Calindol is an activator of the calcium-sensing receptor (CaSR).The extracellular calciumsensing receptor (CaSR), a G protein-coupled receptor (GPCR), senses extracellular calcium[Ca2+]e and regulates calciumion homeostasis.

Calindol (hydrochloride)

C5329-25 25 mg
EUR 1082.4
Description: Calindol is an activator of the calcium-sensing receptor (CaSR).The extracellular calciumsensing receptor (CaSR), a G protein-coupled receptor (GPCR), senses extracellular calcium[Ca2+]e and regulates calciumion homeostasis.

Calindol (hydrochloride)

C5329-5 5 mg
EUR 324
Description: Calindol is an activator of the calcium-sensing receptor (CaSR).The extracellular calciumsensing receptor (CaSR), a G protein-coupled receptor (GPCR), senses extracellular calcium[Ca2+]e and regulates calciumion homeostasis.

Kasugamycin (hydrochloride)

C5503-10000 10 g
EUR 420
Description: Kasugamycin is an aminoglycosidic antibiotic. Aminoglycoside, a medicinal and bacteriologic category of traditional Gram-negative antibacterial therapeutic agent, inhibits protein synthesis and contains as a portion of the molecule an amino-modified glycoside.

Kasugamycin (hydrochloride)

C5503-5000 5 g
EUR 301.2
Description: Kasugamycin is an aminoglycosidic antibiotic. Aminoglycoside, a medicinal and bacteriologic category of traditional Gram-negative antibacterial therapeutic agent, inhibits protein synthesis and contains as a portion of the molecule an amino-modified glycoside.

Ciprofloxacin (hydrochloride)

C5539-10000 10 g
EUR 139.2
Description: Ciprofloxacin (hydrochloride) is a fluoroquinolone antibiotic that has antimicrobial and immunomodulatory activities [1].

Ciprofloxacin (hydrochloride)

C5539-25000 25 g
EUR 184.8
Description: Ciprofloxacin (hydrochloride) is a fluoroquinolone antibiotic that has antimicrobial and immunomodulatory activities [1].

Ciprofloxacin (hydrochloride)

C5539-50000 50 g
EUR 268.8
Description: Ciprofloxacin (hydrochloride) is a fluoroquinolone antibiotic that has antimicrobial and immunomodulatory activities [1].

Fendiline (hydrochloride)

C5675-5000 5 g
EUR 146.4
Description: Fendiline is an ?2-adrenergic receptor antagonist and L-type calcium channel blocker [1,2].The ?2 adrenergic receptor is a G protein-coupled receptor (GPCR). Until now, three different ?2-receptor subtypes have been identified: ?2A, ?2B, and ?2C.

Daunorubicin Hydrochloride

ADC-P-011 unit Ask for price

Doxorubicin hydrochloride

ADC-P-014 unit Ask for price

MMAD hydrochloride

ADC-P-019 unit Ask for price

MMAF Hydrochloride

ADC-P-021 unit Ask for price

Taltobulin hydrochloride

ADC-P-027 unit Ask for price

Moxifloxacin hydrochloride

E1KS1465 50mg
EUR 296.4

(±)-Salsolinol (hydrochloride)

C4364-500 500 mg
EUR 369.6
Description: (±)-Salsolinol targets depolarize dopamineric neurons. Dopaminergic neurons produce dopamine, a neurotransmitter with various roles in neurological functions.

Midodrine (hydrochloride)

C4493-100 100 mg
EUR 135.6
Description: Ki: 2, 6.9, and 1.7 ?M for ?1A, ?1B, ?1D, respectivelyMidodrine is the prodrug of the ?1-adrenergic receptor agonist, 1-(2?,5?-dimethoxyphenyl)-2-aminoethanol.

Midodrine (hydrochloride)

C4493-250 250 mg
EUR 240
Description: Ki: 2, 6.9, and 1.7 ?M for ?1A, ?1B, ?1D, respectivelyMidodrine is the prodrug of the ?1-adrenergic receptor agonist, 1-(2?,5?-dimethoxyphenyl)-2-aminoethanol.

Celiprolol (hydrochloride)

C4521-10 10 mg
EUR 304.8
Description: Celiprolol is a ?1 adrenergic receptor antagonist and ?2 adrenergic receptor partial agonist.?2 adrenergic receptor agonists, also known as adrenergic ?2 receptor agonists, are a class of drugs acting on the ?2 adrenergic receptor.

Celiprolol (hydrochloride)

C4521-25 25 mg
EUR 600
Description: Celiprolol is a ?1 adrenergic receptor antagonist and ?2 adrenergic receptor partial agonist.?2 adrenergic receptor agonists, also known as adrenergic ?2 receptor agonists, are a class of drugs acting on the ?2 adrenergic receptor.

Celiprolol (hydrochloride)

C4521-5 5 mg
EUR 219.6
Description: Celiprolol is a ?1 adrenergic receptor antagonist and ?2 adrenergic receptor partial agonist.?2 adrenergic receptor agonists, also known as adrenergic ?2 receptor agonists, are a class of drugs acting on the ?2 adrenergic receptor.

Aceclidine (hydrochloride)

C4635-1000 1 g
EUR 393.6