3A Plastik

(Bardak.tabak,çatal.ka??k,plastik kap)

Cell culture-derived influenza vaccines in the severe 2017-2018 epidemic season: a step towards improved influenza vaccine effectiveness.

The 2017-2018 seasonal influenza epidemics are severe in the US and Australia where A (H3N2) virus subtype dominated. Although circulating A (H3N2) virus antigen is not different from that recommended by the WHO for vaccine production, the overall interim estimate of vaccine effectiveness was under the historical average (33%) for A (H3N2) virus. The majority (USA) or all (Australia) dose of vaccine contains several amino acid changes in the hemagglutinin protein, which is produced from the necessary adaptation of the virus to embryonated chicken eggs used to manufacture the vaccine most. Previous reports have suggested the potential negative impact of the substitution of egg-driven performance of the vaccine. With the support of Barda, two vaccines licensed in the US is produced in cell culture: a recombinant influenza vaccine (RIV, Flublok ™) produced in insect cells and inactivated vaccines adult mammalian cells (ccIIV, Flucelvax ™). CcIIV quadrivalent (ccIIV4) vaccine for the 2017-2018 influenza season was produced using seed virus A (H3N2) distributed exclusively in cell culture and therefore less adaptative changes eggs. ccIIV dose fairly distributed (but not RIV dose) to allow the initial estimates of higher efficacy relative to traditional egg-based vaccine, the study details pending. The increased availability of certain product comparison vaccine effectiveness estimates for cell-based vaccine and egg-based can provide important clues to inform vaccine product improvements moving forward.

Diclofenac Diethylamine
B1928-50 50 mg
EUR 153.6
Description: Diclofenac diethylamine is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.

Diclofenac Diethylamine
B1928-S Evaluation Sample
EUR 97.2
Description: Diclofenac diethylamine is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.

Diclofenac (diethylamine)
HY-15036A 10mM/1mL
EUR 135.6

DIETHYLAMINE PHOSPHATE
504015 each Ask for price

2‐AMINO ACETAMIDE HYDROCHLORIDE (GLYCINAMIDE HYDROCHLORIDE)
101003 each Ask for price

Acriflavine Hydrochloride
A019-10G 10 g
EUR 66

Acriflavine Hydrochloride
A019-25G 25 g
EUR 94.8

Amodiaquine hydrochloride
A085-5G 5 g
EUR 66

Amastatin . hydrochloride
10-016 5 mg
EUR 440.88
Description: Slow, tight binding and competitive aminopeptidase (AP) inhibitor. Inhibits cytosolic leucine aminopeptidase, microsomal aminopeptidase M and bacterial leucine aminopeptidase, human serum aminopeptidase A (AP-A), aminopeptidase N (AP-N), tyrosine aminopeptidase, but not aminopeptidase B (AP-B). Amastatin is without effect on trypsin, papain, chymotrypsin, elastase, pepsin or thermolysin. Inhibits completely the Suc-Ala-Ala-Pro-Leu-pNA amidolytic enzyme. Slightly inhibits the formation of angiotensin III (Ang III) from Angiotensin II through AP-A, but significantly increases the potency of angiotensin III and [des-Asp1]-angiotensin I. Moderate inhibitor of mitochondrial intermediate peptidase (MIP). Weak inhibitor of simian immunodeficiency virus protease (SIV-PR). ANPEP (aminopeptidase N) is a host receptor targeted by porcine epidemic diarrhoea virus, human coronavirus 229E, feline coronavirus, canine coronavirus, transmissible gastroenteritis virus and infectious bronchitis virus. These viruses all belong to coronaviridae. ANPEP is therefore investigated as a potential target for SARS-CoV-2 infections.

Tetracycline Hydrochloride
A2517-5.1 10 mM (in 1mL DMSO)
EUR 129.6
Description: antibiotictoxicstore at -20°C, warm to room temperature before usesoluble in water at 10mg/mlsoluble in ethanol at 5mg/ml

Tetracycline Hydrochloride
A2517-50 50 mg
EUR 157.2
Description: antibiotictoxicstore at -20°C, warm to room temperature before usesoluble in water at 10mg/mlsoluble in ethanol at 5mg/ml

Alosetron Hydrochloride
A3159-10 10 mg
EUR 129.6
Description: Alosetron is s Serotonin 5HT3-receptor antagonist that is used in treatment of irritable bowel syndrome.

Alosetron Hydrochloride
A3159-5.1 10 mM (in 1mL DMSO)
EUR 129.6
Description: Alosetron is s Serotonin 5HT3-receptor antagonist that is used in treatment of irritable bowel syndrome.

Alosetron Hydrochloride
A3159-50 50 mg
EUR 268.8
Description: Alosetron is s Serotonin 5HT3-receptor antagonist that is used in treatment of irritable bowel syndrome.

Asenapine hydrochloride
A3192-10 10 mg
EUR 166.8
Description: Asenapine is a new atypical antipsychotic developed for the treatment of schizophrenia and acute mania associated with bipolar disorder. Asenapine shows high affinity (pKi) for numerous receptors.

Asenapine hydrochloride
A3192-100 100 mg
EUR 514.8
Description: Asenapine is a new atypical antipsychotic developed for the treatment of schizophrenia and acute mania associated with bipolar disorder. Asenapine shows high affinity (pKi) for numerous receptors.

Asenapine hydrochloride
A3192-5.1 10 mM (in 1mL DMSO)
EUR 180
Description: Asenapine is a new atypical antipsychotic developed for the treatment of schizophrenia and acute mania associated with bipolar disorder. Asenapine shows high affinity (pKi) for numerous receptors.

Asenapine hydrochloride
A3192-50 50 mg
EUR 320.4
Description: Asenapine is a new atypical antipsychotic developed for the treatment of schizophrenia and acute mania associated with bipolar disorder. Asenapine shows high affinity (pKi) for numerous receptors.

AT7519 Hydrochloride
A3197-10 10 mg
EUR 223.2
Description: IC50: AT7519 showed potent antiproliferative activity (40-940 nmol/L) in a panel of human tumor cell lines.Cyclin-dependent kinases (CDK) play a central role in the growth, division, and death of eukaryotic cell.

AT7519 Hydrochloride
A3197-100 100 mg
EUR 512.4
Description: IC50: AT7519 showed potent antiproliferative activity (40-940 nmol/L) in a panel of human tumor cell lines.Cyclin-dependent kinases (CDK) play a central role in the growth, division, and death of eukaryotic cell.

AT7519 Hydrochloride
A3197-5 5 mg
EUR 166.8
Description: IC50: AT7519 showed potent antiproliferative activity (40-940 nmol/L) in a panel of human tumor cell lines.Cyclin-dependent kinases (CDK) play a central role in the growth, division, and death of eukaryotic cell.

AT7519 Hydrochloride
A3197-5.1 10 mM (in 1mL DMSO)
EUR 180
Description: IC50: AT7519 showed potent antiproliferative activity (40-940 nmol/L) in a panel of human tumor cell lines.Cyclin-dependent kinases (CDK) play a central role in the growth, division, and death of eukaryotic cell.

AT7519 Hydrochloride
A3197-50 50 mg
EUR 404.4
Description: IC50: AT7519 showed potent antiproliferative activity (40-940 nmol/L) in a panel of human tumor cell lines.Cyclin-dependent kinases (CDK) play a central role in the growth, division, and death of eukaryotic cell.

Atrasentan hydrochloride
A3201-10 10 mg
EUR 710.4
Description: Description:IC50 Value: 0.0551 nM (for ET A receptor) [1]Atrasentan (A-147627) is an endothelin receptor antagonist being developed at Abbott Laboratories for the treatment of prostate cancer.

Atrasentan hydrochloride
A3201-5 5 mg
EUR 451.2
Description: Description:IC50 Value: 0.0551 nM (for ET A receptor) [1]Atrasentan (A-147627) is an endothelin receptor antagonist being developed at Abbott Laboratories for the treatment of prostate cancer.

Atrasentan hydrochloride
A3201-5.1 10 mM (in 1mL DMSO)
EUR 529.2
Description: Description:IC50 Value: 0.0551 nM (for ET A receptor) [1]Atrasentan (A-147627) is an endothelin receptor antagonist being developed at Abbott Laboratories for the treatment of prostate cancer.

Atrasentan hydrochloride
A3201-50 50 mg
EUR 2025.6
Description: Description:IC50 Value: 0.0551 nM (for ET A receptor) [1]Atrasentan (A-147627) is an endothelin receptor antagonist being developed at Abbott Laboratories for the treatment of prostate cancer.

BMS345541 hydrochloride
A3248-10 10 mg
EUR 282
Description: BMS-345541 is a highly selective inhibitor of IKK-1 and IKK-2 with IC50 values of 4?M and 0.3?M, respectively [1].BMS-345541 is a highly selective inhibitor of IKK that inhibits NF-?B-dependent transcription of pro-inflammatory cytokines both in vitro and in vivo.

BMS345541 hydrochloride
A3248-5 5 mg
EUR 205.2
Description: BMS-345541 is a highly selective inhibitor of IKK-1 and IKK-2 with IC50 values of 4?M and 0.3?M, respectively [1].BMS-345541 is a highly selective inhibitor of IKK that inhibits NF-?B-dependent transcription of pro-inflammatory cytokines both in vitro and in vivo.

BMS345541 hydrochloride
A3248-50 50 mg
EUR 714
Description: BMS-345541 is a highly selective inhibitor of IKK-1 and IKK-2 with IC50 values of 4?M and 0.3?M, respectively [1].BMS-345541 is a highly selective inhibitor of IKK that inhibits NF-?B-dependent transcription of pro-inflammatory cytokines both in vitro and in vivo.

CCT241533 hydrochloride
A3292-1 1 mg
EUR 147.6
Description: CHK2 is a checkpoint kinase involved in the ATM-mediated response to double-strand DNA breaks. Inhibitors of CHK2 may increase the efficacy of genotoxic cancer therapies. CCT241533 has been identified and characterized as a novel CHK2 kinase inhibitor.

CCT241533 hydrochloride
A3292-10 10 mg
EUR 528
Description: CHK2 is a checkpoint kinase involved in the ATM-mediated response to double-strand DNA breaks. Inhibitors of CHK2 may increase the efficacy of genotoxic cancer therapies. CCT241533 has been identified and characterized as a novel CHK2 kinase inhibitor.

CCT241533 hydrochloride
A3292-5 5 mg
EUR 386.4
Description: CHK2 is a checkpoint kinase involved in the ATM-mediated response to double-strand DNA breaks. Inhibitors of CHK2 may increase the efficacy of genotoxic cancer therapies. CCT241533 has been identified and characterized as a novel CHK2 kinase inhibitor.

Clemizole hydrochloride
A3316-10 10 mg
EUR 170.4
Description: IC50: 8 mM (NS4B) The NS4B protein is a key player in HCV replication. Disrupting NS4B function thus represents an attractive new anti-HCV strategy.

Clemizole hydrochloride
A3316-100 100 mg
EUR 727.2
Description: IC50: 8 mM (NS4B) The NS4B protein is a key player in HCV replication. Disrupting NS4B function thus represents an attractive new anti-HCV strategy.

Clemizole hydrochloride
A3316-5 5 mg
EUR 129.6
Description: IC50: 8 mM (NS4B) The NS4B protein is a key player in HCV replication. Disrupting NS4B function thus represents an attractive new anti-HCV strategy.

Clemizole hydrochloride
A3316-5.1 10 mM (in 1mL DMSO)
EUR 142.8
Description: IC50: 8 mM (NS4B) The NS4B protein is a key player in HCV replication. Disrupting NS4B function thus represents an attractive new anti-HCV strategy.

Clemizole hydrochloride
A3316-50 50 mg
EUR 477.6
Description: IC50: 8 mM (NS4B) The NS4B protein is a key player in HCV replication. Disrupting NS4B function thus represents an attractive new anti-HCV strategy.

Elacridar hydrochloride
A3385-10 10 mg
EUR 224.4
Description: Elacridar is an inhibitor of breast cancer resistance protein (BCRP) and P-glycoprotein (P-GP) that has been used to improve the brain distribution of drugs. Recent studies have revealed that elacridar could probably be the substrate of these multidrug transporters (MDTs) [2].

Elacridar hydrochloride
A3385-100 100 mg
EUR 1015.2
Description: Elacridar is an inhibitor of breast cancer resistance protein (BCRP) and P-glycoprotein (P-GP) that has been used to improve the brain distribution of drugs. Recent studies have revealed that elacridar could probably be the substrate of these multidrug transporters (MDTs) [2].

Elacridar hydrochloride
A3385-50 50 mg
EUR 598.8
Description: Elacridar is an inhibitor of breast cancer resistance protein (BCRP) and P-glycoprotein (P-GP) that has been used to improve the brain distribution of drugs. Recent studies have revealed that elacridar could probably be the substrate of these multidrug transporters (MDTs) [2].

Etifoxine hydrochloride
A3401-10 10 mg
EUR 180
Description: Etifoxine is potentiator of GABAA receptor function in cultured neurons. Etifoxine preferentially acts on ?2 or ?3 subunit-containing GABAA receptors. Etifoxine exhibits anxiolytic activity in rodents and humans with no sedative, myorelaxant or mnesic side effects.

Etifoxine hydrochloride
A3401-50 50 mg
EUR 536.4
Description: Etifoxine is potentiator of GABAA receptor function in cultured neurons. Etifoxine preferentially acts on ?2 or ?3 subunit-containing GABAA receptors. Etifoxine exhibits anxiolytic activity in rodents and humans with no sedative, myorelaxant or mnesic side effects.

Gefitinib hydrochloride
A3433-100 100 mg
EUR 205.2
Description: The EGFR is a Mr 170,000 transmembrane glycoprotein with an external binding domain and an intracellular tyrosine kinase domain. Gefitinib (ZD-1839, Iressa) is an Epidermal Growth Factor Receptor-selective Tyrosine Kinase Inhibitor.

Gefitinib hydrochloride
A3433-250 250 mg
EUR 324
Description: The EGFR is a Mr 170,000 transmembrane glycoprotein with an external binding domain and an intracellular tyrosine kinase domain. Gefitinib (ZD-1839, Iressa) is an Epidermal Growth Factor Receptor-selective Tyrosine Kinase Inhibitor.

Guanfacine hydrochloride
A3451-10 10 mg
EUR 130.8
Description: Guanfacine, an anti-hypertensive agent, is a selective agonist of ?2A-adrenoceptor (?2AR) with a Kd value of 31 nM, displaying 60-fold selectivity over ?2B-adrenoceptors.

Guanfacine hydrochloride
A3451-5.1 10 mM (in 1mL DMSO)
EUR 129.6
Description: Guanfacine, an anti-hypertensive agent, is a selective agonist of ?2A-adrenoceptor (?2AR) with a Kd value of 31 nM, displaying 60-fold selectivity over ?2B-adrenoceptors.

Guanfacine hydrochloride
A3451-50 50 mg
EUR 315.6
Description: Guanfacine, an anti-hypertensive agent, is a selective agonist of ?2A-adrenoceptor (?2AR) with a Kd value of 31 nM, displaying 60-fold selectivity over ?2B-adrenoceptors.

Hydroxyfasudil hydrochloride
A3479-10 10 mg
EUR 271.2
Description: Description:IC50 Value: 0.12 uM (ROCK1); 0.17 uM (ROCK2) [1]Hydroxyfasudil, metabolite of Fasudil, is a potent Rho-kinase inhibitor and vasodilator.

Hydroxyfasudil hydrochloride
A3479-50 50 mg
EUR 703.2
Description: Description:IC50 Value: 0.12 uM (ROCK1); 0.17 uM (ROCK2) [1]Hydroxyfasudil, metabolite of Fasudil, is a potent Rho-kinase inhibitor and vasodilator.

Icotinib Hydrochloride
A3482-10 10 mg
EUR 240
Description: Icotinib Hydrochloride is a potent and highly selective inhibitor of epidermal growth factor receptor tyrosine kinases (EGFR-TKI) with IC50 value of 5 nM.

Icotinib Hydrochloride
A3482-5 5 mg
EUR 186
Description: Icotinib Hydrochloride is a potent and highly selective inhibitor of epidermal growth factor receptor tyrosine kinases (EGFR-TKI) with IC50 value of 5 nM.

Icotinib Hydrochloride
A3482-5.1 10 mM (in 1mL DMSO)
EUR 199.2
Description: Icotinib Hydrochloride is a potent and highly selective inhibitor of epidermal growth factor receptor tyrosine kinases (EGFR-TKI) with IC50 value of 5 nM.

Icotinib Hydrochloride
A3482-50 50 mg
EUR 584.4
Description: Icotinib Hydrochloride is a potent and highly selective inhibitor of epidermal growth factor receptor tyrosine kinases (EGFR-TKI) with IC50 value of 5 nM.

Imatinib hydrochloride
A3487-100 100 mg
EUR 157.2
Description: Description:IC50 Value: 100 nM (PDGFR) [1]; 100 nM (c-Kit) [2]Imatinib is a multi-target inhibitor of v-Abl, c-Kit and PDGFR with IC50 of 0.6 ?M, 0.1 ?M and 0.1 ?M, respectively.

Istaroxime hydrochloride
A3508-10 10 mg
EUR 564
Description: Istaroxime hydrochloride(PST2744) is a novel inhibitor of Na+/K+-ATPase with IC50 value of 0.43±0.15?M [1].

Istaroxime hydrochloride
A3508-100 100 mg
EUR 2203.2
Description: Istaroxime hydrochloride(PST2744) is a novel inhibitor of Na+/K+-ATPase with IC50 value of 0.43±0.15?M [1].

Istaroxime hydrochloride
A3508-2 2 mg
EUR 278.4
Description: Istaroxime hydrochloride(PST2744) is a novel inhibitor of Na+/K+-ATPase with IC50 value of 0.43±0.15?M [1].

Istaroxime hydrochloride
A3508-5 5 mg
EUR 390
Description: Istaroxime hydrochloride(PST2744) is a novel inhibitor of Na+/K+-ATPase with IC50 value of 0.43±0.15?M [1].

Istaroxime hydrochloride
A3508-50 50 mg
EUR 1476
Description: Istaroxime hydrochloride(PST2744) is a novel inhibitor of Na+/K+-ATPase with IC50 value of 0.43±0.15?M [1].

PJ34 hydrochloride
A4159-10 10 mg
EUR 142.8
Description: PJ34 is a novel and potent inhibitor of poly(ADP-ribose) polymerase (PARP), an enzyme involved in DNA repair and cell proliferation, that dose-dependently inhibits purified PARP enzyme in a cell-free assay with half maximal effective concentration EC50 value of 20 nM.

PJ34 hydrochloride
A4159-5 5 mg
EUR 129.6
Description: PJ34 is a novel and potent inhibitor of poly(ADP-ribose) polymerase (PARP), an enzyme involved in DNA repair and cell proliferation, that dose-dependently inhibits purified PARP enzyme in a cell-free assay with half maximal effective concentration EC50 value of 20 nM.

PJ34 hydrochloride
A4159-5.1 10 mM (in 1mL DMSO)
EUR 150
Description: PJ34 is a novel and potent inhibitor of poly(ADP-ribose) polymerase (PARP), an enzyme involved in DNA repair and cell proliferation, that dose-dependently inhibits purified PARP enzyme in a cell-free assay with half maximal effective concentration EC50 value of 20 nM.

PJ34 hydrochloride
A4159-50 50 mg
EUR 296.4
Description: PJ34 is a novel and potent inhibitor of poly(ADP-ribose) polymerase (PARP), an enzyme involved in DNA repair and cell proliferation, that dose-dependently inhibits purified PARP enzyme in a cell-free assay with half maximal effective concentration EC50 value of 20 nM.

PJ34 hydrochloride
A4159-S Evaluation Sample
EUR 97.2
Description: PJ34 is a novel and potent inhibitor of poly(ADP-ribose) polymerase (PARP), an enzyme involved in DNA repair and cell proliferation, that dose-dependently inhibits purified PARP enzyme in a cell-free assay with half maximal effective concentration EC50 value of 20 nM.

RETRA hydrochloride
A4485-10 10 mg
EUR 369.6
Description: IC50: Inhibit tumor cells growth with an IC50of about 4 M.Being defective for the tumor-suppressor function, mutant p53, a major contributor to malignancy, exerts oncogenic activity also by blocking another tumor-suppressing protein - p73.

RETRA hydrochloride
A4485-50 50 mg
EUR 1363.2
Description: IC50: Inhibit tumor cells growth with an IC50of about 4 M.Being defective for the tumor-suppressor function, mutant p53, a major contributor to malignancy, exerts oncogenic activity also by blocking another tumor-suppressing protein - p73.

Thiamine Hydrochloride
20-abx082137
  • EUR 276.00
  • EUR 226.80
  • 100 g
  • 25 g

Vancomycin hydrochloride
20-abx082225
  • EUR 243.60
  • EUR 460.80
  • 100 mg
  • 1 g

Pyridoxine hydrochloride
abx082298-25g 25 g
EUR 260.4

Thiamine Hydrochloride
20-abx082339
  • EUR 309.60
  • EUR 226.80
  • 100 g
  • 25 g

Betaine Hydrochloride
abx082532-100g 100 g
EUR 243.6

Vancomycin hydrochloride
20-abx082574
  • EUR 243.60
  • EUR 410.40
  • 100 mg
  • 1 g

Thiamine Hydrochloride
abx082609-25kg 25 kg
EUR 6307.2

Doxorubicin Hydrochloride
20-abx076623
  • EUR 410.40
  • EUR 944.40
  • 10 mg
  • 50 mg

Erlotinib Hydrochloride
20-abx076664
  • EUR 427.20
  • EUR 276.00
  • 100 mg
  • 10 mg

FTY720 Hydrochloride
20-abx076665
  • EUR 427.20
  • EUR 276.00
  • 25 mg
  • 5 mg

Terazosin Hydrochloride
20-abx076677
  • EUR 493.20
  • EUR 292.80
  • 100 mg
  • 20 mg

GSK690693 Hydrochloride
20-abx076782
  • EUR 1011.60
  • EUR 410.40
  • 25 mg
  • 5 mg

Amiodarone Hydrochloride
abx076829-1g 1 g
EUR 326.4

Metformin Hydrochloride
abx076830-5g 5 g
EUR 276

Bestatin hydrochloride
A8621-10 10 mg
EUR 157.2
Description: Bestatin hydrochloride, also known as Ubenimex, is an inhibitor of aminopeptidase B and N (APN)/CD13 [1].Bestatin, an antibiotic of microbial origin, is a potent inhibitor of some aminopeptidases which can be administered to cultured cells, intact animals and humans with low toxicity.

Bestatin hydrochloride
A8621-100 100 mg
EUR 532.8
Description: Bestatin hydrochloride, also known as Ubenimex, is an inhibitor of aminopeptidase B and N (APN)/CD13 [1].Bestatin, an antibiotic of microbial origin, is a potent inhibitor of some aminopeptidases which can be administered to cultured cells, intact animals and humans with low toxicity.

Bestatin hydrochloride
A8621-25 25 mg
EUR 226.8
Description: Bestatin hydrochloride, also known as Ubenimex, is an inhibitor of aminopeptidase B and N (APN)/CD13 [1].Bestatin, an antibiotic of microbial origin, is a potent inhibitor of some aminopeptidases which can be administered to cultured cells, intact animals and humans with low toxicity.

Bestatin hydrochloride
A8621-5 5 mg
EUR 129.6
Description: Bestatin hydrochloride, also known as Ubenimex, is an inhibitor of aminopeptidase B and N (APN)/CD13 [1].Bestatin, an antibiotic of microbial origin, is a potent inhibitor of some aminopeptidases which can be administered to cultured cells, intact animals and humans with low toxicity.

Flavopiridol hydrochloride
A8640-10 10 mg
EUR 129.6
Description: Flavopiridol hydrochloride is a selective inhibitor of CDK1, CDK2, CDK4 and CDK6 with IC50 value all ~41 nM as well as CDK7 with 300nM [1] [2] [3].CDKs are protein kinase families which involve in the process of regulating transcription, mRNA processing, cell differentiation and cell cycle.

Flavopiridol hydrochloride
A8640-100 100 mg
EUR 528
Description: Flavopiridol hydrochloride is a selective inhibitor of CDK1, CDK2, CDK4 and CDK6 with IC50 value all ~41 nM as well as CDK7 with 300nM [1] [2] [3].CDKs are protein kinase families which involve in the process of regulating transcription, mRNA processing, cell differentiation and cell cycle.

Flavopiridol hydrochloride
A8640-1000 1 g
EUR 3259.2
Description: Flavopiridol hydrochloride is a selective inhibitor of CDK1, CDK2, CDK4 and CDK6 with IC50 value all ~41 nM as well as CDK7 with 300nM [1] [2] [3].CDKs are protein kinase families which involve in the process of regulating transcription, mRNA processing, cell differentiation and cell cycle.

Flavopiridol hydrochloride
A8640-25 25 mg
EUR 199.2
Description: Flavopiridol hydrochloride is a selective inhibitor of CDK1, CDK2, CDK4 and CDK6 with IC50 value all ~41 nM as well as CDK7 with 300nM [1] [2] [3].CDKs are protein kinase families which involve in the process of regulating transcription, mRNA processing, cell differentiation and cell cycle.

Flavopiridol hydrochloride
A8640-5.1 10 mM (in 1mL DMSO)
EUR 129.6
Description: Flavopiridol hydrochloride is a selective inhibitor of CDK1, CDK2, CDK4 and CDK6 with IC50 value all ~41 nM as well as CDK7 with 300nM [1] [2] [3].CDKs are protein kinase families which involve in the process of regulating transcription, mRNA processing, cell differentiation and cell cycle.

Acriflavine Hydrochloride
AB4433 25g
EUR 79.84

PD153035 hydrochloride
A8199-10 10 mg
EUR 141.6
Description: PD153035, a tyrosine kinase inhibitor, prevents epidermal growth factor receptor activation and inhibits growth of cancer cells in a receptor number-dependent manner.

PD153035 hydrochloride
A8199-5.1 10 mM (in 1mL DMSO)
EUR 150
Description: PD153035, a tyrosine kinase inhibitor, prevents epidermal growth factor receptor activation and inhibits growth of cancer cells in a receptor number-dependent manner.

PD153035 hydrochloride
A8199-50 50 mg
EUR 404.4
Description: PD153035, a tyrosine kinase inhibitor, prevents epidermal growth factor receptor activation and inhibits growth of cancer cells in a receptor number-dependent manner.

PD153035 hydrochloride
A8199-S Evaluation Sample
EUR 97.2
Description: PD153035, a tyrosine kinase inhibitor, prevents epidermal growth factor receptor activation and inhibits growth of cancer cells in a receptor number-dependent manner.

Erlotinib Hydrochloride
A8234-1000 1 g
EUR 129.6
Description: Erlotinib hydrochloride (the trade name Tarceva?) is a directly acting inhibitor of epidermal growth factor receptor (EGFR/HER-1) tyrosine kinase with an IC50 of 2 nM.Epidermal growth factor receptor (EGFR) is one member of the ErbB family which includes EGFR (ErbB1), ErbB2, ErbB3 and ErbB4.

Erlotinib Hydrochloride
A8234-5.1 10 mM (in 1mL DMSO)
EUR 135.6
Description: Erlotinib hydrochloride (the trade name Tarceva?) is a directly acting inhibitor of epidermal growth factor receptor (EGFR/HER-1) tyrosine kinase with an IC50 of 2 nM.Epidermal growth factor receptor (EGFR) is one member of the ErbB family which includes EGFR (ErbB1), ErbB2, ErbB3 and ErbB4.

Erlotinib Hydrochloride
A8234-5000 5 g
EUR 309.6
Description: Erlotinib hydrochloride (the trade name Tarceva?) is a directly acting inhibitor of epidermal growth factor receptor (EGFR/HER-1) tyrosine kinase with an IC50 of 2 nM.Epidermal growth factor receptor (EGFR) is one member of the ErbB family which includes EGFR (ErbB1), ErbB2, ErbB3 and ErbB4.

Pazopanib Hydrochloride
A8347-100 100 mg
EUR 268.8
Description: Pazopanib HCl is a receptor tyrosine kinase inhibitor that targets multiple kinases, including VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit, and c-Fms, with IC50s 10nM, 30nM, 47nM, 84nM, 74nM, 140nM, and 146nM respectively [1-3].

Pazopanib Hydrochloride
A8347-25 25 mg
EUR 129.6
Description: Pazopanib HCl is a receptor tyrosine kinase inhibitor that targets multiple kinases, including VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit, and c-Fms, with IC50s 10nM, 30nM, 47nM, 84nM, 74nM, 140nM, and 146nM respectively [1-3].

Pazopanib Hydrochloride
A8347-5.1 10 mM (in 1mL DMSO)
EUR 135.6
Description: Pazopanib HCl is a receptor tyrosine kinase inhibitor that targets multiple kinases, including VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit, and c-Fms, with IC50s 10nM, 30nM, 47nM, 84nM, 74nM, 140nM, and 146nM respectively [1-3].

Pazopanib Hydrochloride
A8347-500 500 mg
EUR 727.2
Description: Pazopanib HCl is a receptor tyrosine kinase inhibitor that targets multiple kinases, including VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit, and c-Fms, with IC50s 10nM, 30nM, 47nM, 84nM, 74nM, 140nM, and 146nM respectively [1-3].

Pazopanib Hydrochloride
A8347-S Evaluation Sample
EUR 97.2
Description: Pazopanib HCl is a receptor tyrosine kinase inhibitor that targets multiple kinases, including VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit, and c-Fms, with IC50s 10nM, 30nM, 47nM, 84nM, 74nM, 140nM, and 146nM respectively [1-3].

LDN193189 Hydrochloride
A3545-10 10 mg
EUR 282
Description: LDN193189 is a selective transcriptional activity morphogenetic protein (BMP) type I receptors inhibitor. It inhibits activin receptor-like kinase-2 (ALK2) and ALK3 with IC50 values of 5 nM and 30 nM, respectively [1].

LDN193189 Hydrochloride
A3545-5 5 mg
EUR 177.6
Description: LDN193189 is a selective transcriptional activity morphogenetic protein (BMP) type I receptors inhibitor. It inhibits activin receptor-like kinase-2 (ALK2) and ALK3 with IC50 values of 5 nM and 30 nM, respectively [1].

LDN193189 Hydrochloride
A3545-5.1 10 mM (in 1mL DMSO)
EUR 268.8
Description: LDN193189 is a selective transcriptional activity morphogenetic protein (BMP) type I receptors inhibitor. It inhibits activin receptor-like kinase-2 (ALK2) and ALK3 with IC50 values of 5 nM and 30 nM, respectively [1].

LDN193189 Hydrochloride
A3545-50 50 mg
EUR 895.2
Description: LDN193189 is a selective transcriptional activity morphogenetic protein (BMP) type I receptors inhibitor. It inhibits activin receptor-like kinase-2 (ALK2) and ALK3 with IC50 values of 5 nM and 30 nM, respectively [1].

LDN193189 Hydrochloride
A3545-S Evaluation Sample
EUR 97.2
Description: LDN193189 is a selective transcriptional activity morphogenetic protein (BMP) type I receptors inhibitor. It inhibits activin receptor-like kinase-2 (ALK2) and ALK3 with IC50 values of 5 nM and 30 nM, respectively [1].

Lenalidomide hydrochloride
A3547-100 100 mg
EUR 226.8
Description: IC50 Value: 13 nM [1] Lenalidomideis a derivative of thalidomide introduced in 2004. Lenalidomide (Revlimid, CC-5013) is a TNF-? secretion inhibitor with IC50 of 13 nM. in vitro: Lenalidomide strongly induces IL-2 and sIL-2R production.

Lenalidomide hydrochloride
A3547-250 250 mg
EUR 268.8
Description: IC50 Value: 13 nM [1] Lenalidomideis a derivative of thalidomide introduced in 2004. Lenalidomide (Revlimid, CC-5013) is a TNF-? secretion inhibitor with IC50 of 13 nM. in vitro: Lenalidomide strongly induces IL-2 and sIL-2R production.

Lenalidomide hydrochloride
A3547-50 50 mg
EUR 184.8
Description: IC50 Value: 13 nM [1] Lenalidomideis a derivative of thalidomide introduced in 2004. Lenalidomide (Revlimid, CC-5013) is a TNF-? secretion inhibitor with IC50 of 13 nM. in vitro: Lenalidomide strongly induces IL-2 and sIL-2R production.

Lenalidomide hydrochloride
A3547-500 500 mg
EUR 309.6
Description: IC50 Value: 13 nM [1] Lenalidomideis a derivative of thalidomide introduced in 2004. Lenalidomide (Revlimid, CC-5013) is a TNF-? secretion inhibitor with IC50 of 13 nM. in vitro: Lenalidomide strongly induces IL-2 and sIL-2R production.

Mefloquine hydrochloride
A3593-100 100 mg
EUR 135.6
Description: Description:IC50 Value: 1 microM ( for K+ channel) [1]Mefloquine is a quinoline antimalarial drug that is structurally related to the antiarrhythmic agent quinidine. Mefloquine is widely used in both the treatment and prophylaxis of Plasmodium falciparum malaria.

Mefloquine hydrochloride
A3593-1000 1 g
EUR 456
Description: Description:IC50 Value: 1 microM ( for K+ channel) [1]Mefloquine is a quinoline antimalarial drug that is structurally related to the antiarrhythmic agent quinidine. Mefloquine is widely used in both the treatment and prophylaxis of Plasmodium falciparum malaria.

Mefloquine hydrochloride
A3593-5.1 10 mM (in 1mL DMSO)
EUR 142.8
Description: Description:IC50 Value: 1 microM ( for K+ channel) [1]Mefloquine is a quinoline antimalarial drug that is structurally related to the antiarrhythmic agent quinidine. Mefloquine is widely used in both the treatment and prophylaxis of Plasmodium falciparum malaria.

MPEP Hydrochloride
A3633-10 10 mg
EUR 142.8
Description: IC50: 36 nMMPEP is a potent, selective and systemically active mGlu5 receptor antagonist. Metabotropic glutamate (mGlu) receptors are a of G-protein-coupled receptor family linked to multiple second messengers and modulation of ion channel functions in the nervous system.

MPEP Hydrochloride
A3633-50 50 mg
EUR 379.2
Description: IC50: 36 nMMPEP is a potent, selective and systemically active mGlu5 receptor antagonist. Metabotropic glutamate (mGlu) receptors are a of G-protein-coupled receptor family linked to multiple second messengers and modulation of ion channel functions in the nervous system.

MPTP hydrochloride
A3634-10 10 mg
EUR 162
Description: IC50 Value: 53uM?inhibited the nerve-evoked twitches of phrenic nerve-hemidiaphragm preparations from ICR mice? . MPTP HCl (Sigma-Chem.) induced reduction in the DOPAC HVA/dopamine (DA) ratio and increase in striatal ascorbate (AS) oxidation in rats [1].

MPTP hydrochloride
A3634-50 50 mg
EUR 344.4
Description: IC50 Value: 53uM?inhibited the nerve-evoked twitches of phrenic nerve-hemidiaphragm preparations from ICR mice? . MPTP HCl (Sigma-Chem.) induced reduction in the DOPAC HVA/dopamine (DA) ratio and increase in striatal ascorbate (AS) oxidation in rats [1].

MTEP hydrochloride
A3636-10 10 mg
EUR 205.2
Description: IC50: 5 nMMTEP is a selective metabotropic glutamate receptor subtype 5 (mGluR5) antagonist.The mGluRs are classified into three groups: group I (mGluR1 and 5), group II (mGluR2 and 3) and group III (mGluR4, 6, 7 and 8).

MTEP hydrochloride
A3636-5 5 mg
EUR 153.6
Description: IC50: 5 nMMTEP is a selective metabotropic glutamate receptor subtype 5 (mGluR5) antagonist.The mGluRs are classified into three groups: group I (mGluR1 and 5), group II (mGluR2 and 3) and group III (mGluR4, 6, 7 and 8).

MTEP hydrochloride
A3636-50 50 mg
EUR 686.4
Description: IC50: 5 nMMTEP is a selective metabotropic glutamate receptor subtype 5 (mGluR5) antagonist.The mGluRs are classified into three groups: group I (mGluR1 and 5), group II (mGluR2 and 3) and group III (mGluR4, 6, 7 and 8).

Olprinone Hydrochloride
A3683-100 100 mg
EUR 408
Description: Olprinone is a selective phosphodiesterase 3 (PDE3) inhibitor. Olprinone is used as cardiotonic agent with positive inotropic and vasodilating effects. Olprinone has been reported to improve microcirculation and attenuate inflammation.

Olprinone Hydrochloride
A3683-25 25 mg
EUR 199.2
Description: Olprinone is a selective phosphodiesterase 3 (PDE3) inhibitor. Olprinone is used as cardiotonic agent with positive inotropic and vasodilating effects. Olprinone has been reported to improve microcirculation and attenuate inflammation.

Olprinone Hydrochloride
A3683-500 500 mg
EUR 1104
Description: Olprinone is a selective phosphodiesterase 3 (PDE3) inhibitor. Olprinone is used as cardiotonic agent with positive inotropic and vasodilating effects. Olprinone has been reported to improve microcirculation and attenuate inflammation.

Pitolisant hydrochloride
A3727-10 10 mg
EUR 201.6
Description: Pitolisant HCl (BF2.649; Ciproxidine) is a potent, novel, and selective nonimidazole inverse agonist at the recombinant human H3 receptor with a Ki value of 0.16 nM[1].

Pitolisant hydrochloride
A3727-5.1 10 mM (in 1mL DMSO)
EUR 129.6
Description: Pitolisant HCl (BF2.649; Ciproxidine) is a potent, novel, and selective nonimidazole inverse agonist at the recombinant human H3 receptor with a Ki value of 0.16 nM[1].

Pitolisant hydrochloride
A3727-50 50 mg
EUR 682.8
Description: Pitolisant HCl (BF2.649; Ciproxidine) is a potent, novel, and selective nonimidazole inverse agonist at the recombinant human H3 receptor with a Ki value of 0.16 nM[1].

PRT062607 Hydrochloride
A3736-25 25 mg
EUR 456
Description: PRT062607 Hydrochloride is a highly selective and novel SYK inhibitor with IC50 value of 1 nM. Spleen tyrosine kinase (SYK) is a cytoplasmic tyrosine kinase and primarily expressed in hematopoietic cells including B-cells.

PRT062607 Hydrochloride
A3736-5 5 mg
EUR 224.4
Description: PRT062607 Hydrochloride is a highly selective and novel SYK inhibitor with IC50 value of 1 nM. Spleen tyrosine kinase (SYK) is a cytoplasmic tyrosine kinase and primarily expressed in hematopoietic cells including B-cells.

PRT062607 Hydrochloride
A3736-5.1 10 mM (in 1mL DMSO)
EUR 240
Description: PRT062607 Hydrochloride is a highly selective and novel SYK inhibitor with IC50 value of 1 nM. Spleen tyrosine kinase (SYK) is a cytoplasmic tyrosine kinase and primarily expressed in hematopoietic cells including B-cells.

PRT062607 Hydrochloride
A3736-S Evaluation Sample
EUR 97.2
Description: PRT062607 Hydrochloride is a highly selective and novel SYK inhibitor with IC50 value of 1 nM. Spleen tyrosine kinase (SYK) is a cytoplasmic tyrosine kinase and primarily expressed in hematopoietic cells including B-cells.

Regorafenib hydrochloride
A3750-10 10 mg
EUR 150
Description: Regorafenib (BAY 73-4506) is a multikinase inhibitor with IC50 of 17, 40 and 69 nM c-KIT, VEGFR2, B-Raf.

Regorafenib hydrochloride
A3750-100 100 mg
EUR 282
Description: Regorafenib (BAY 73-4506) is a multikinase inhibitor with IC50 of 17, 40 and 69 nM c-KIT, VEGFR2, B-Raf.

Regorafenib hydrochloride
A3750-200 200 mg
EUR 582
Description: Regorafenib (BAY 73-4506) is a multikinase inhibitor with IC50 of 17, 40 and 69 nM c-KIT, VEGFR2, B-Raf.

Regorafenib hydrochloride
A3750-5.1 10 mM (in 1mL DMSO)
EUR 199.2
Description: Regorafenib (BAY 73-4506) is a multikinase inhibitor with IC50 of 17, 40 and 69 nM c-KIT, VEGFR2, B-Raf.

Regorafenib hydrochloride
A3750-50 50 mg
EUR 199.2
Description: Regorafenib (BAY 73-4506) is a multikinase inhibitor with IC50 of 17, 40 and 69 nM c-KIT, VEGFR2, B-Raf.

Resminostat hydrochloride
A3755-10 10 mg
EUR 428.4
Description: Resminostat is an inhibitor of histone deacetylase (HDAC) with IC50 values of 42.5nM, 50.1nM and 71.8nM, respectively against HDAC1, 3 and 6 [1].

Resminostat hydrochloride
A3755-100 100 mg
EUR 1905.6
Description: Resminostat is an inhibitor of histone deacetylase (HDAC) with IC50 values of 42.5nM, 50.1nM and 71.8nM, respectively against HDAC1, 3 and 6 [1].

Resminostat hydrochloride
A3755-5.1 10 mM (in 1mL DMSO)
EUR 464.4
Description: Resminostat is an inhibitor of histone deacetylase (HDAC) with IC50 values of 42.5nM, 50.1nM and 71.8nM, respectively against HDAC1, 3 and 6 [1].

Resminostat hydrochloride
A3755-50 50 mg
EUR 1209.6
Description: Resminostat is an inhibitor of histone deacetylase (HDAC) with IC50 values of 42.5nM, 50.1nM and 71.8nM, respectively against HDAC1, 3 and 6 [1].

Rimonabant hydrochloride
A3766-10 10 mg
EUR 186
Description: Rimonabant, also known as SR141716, was the first selective central cannabinoid (CB1) receptor inverse agonist (Ki = 1.8 nM) to be developed as an appetite suppressant, anti-obesity drug.

Rimonabant hydrochloride
A3766-100 100 mg
EUR 710.4
Description: Rimonabant, also known as SR141716, was the first selective central cannabinoid (CB1) receptor inverse agonist (Ki = 1.8 nM) to be developed as an appetite suppressant, anti-obesity drug.

Rimonabant hydrochloride
A3766-5.1 10 mM (in 1mL DMSO)
EUR 199.2
Description: Rimonabant, also known as SR141716, was the first selective central cannabinoid (CB1) receptor inverse agonist (Ki = 1.8 nM) to be developed as an appetite suppressant, anti-obesity drug.

Rimonabant hydrochloride
A3766-50 50 mg
EUR 494.4
Description: Rimonabant, also known as SR141716, was the first selective central cannabinoid (CB1) receptor inverse agonist (Ki = 1.8 nM) to be developed as an appetite suppressant, anti-obesity drug.

Rotigotine hydrochloride
A3777-100 100 mg
EUR 480
Description: Rotigotine is dopamine D2 and D3 receptor agonist. Ki values are 13 and 0.71 nM for D2 and D3 respectively. Rotigotine also has significant affinity for 5-HT1A and adrenergic ?2B receptors. Rotigotine exhibits antiparkinsonian acitivity.

Rotigotine hydrochloride
A3777-200 200 mg
EUR 812.4
Description: Rotigotine is dopamine D2 and D3 receptor agonist. Ki values are 13 and 0.71 nM for D2 and D3 respectively. Rotigotine also has significant affinity for 5-HT1A and adrenergic ?2B receptors. Rotigotine exhibits antiparkinsonian acitivity.

Rotigotine hydrochloride
A3777-5.1 10 mM (in 1mL DMSO)
EUR 417.6
Description: Rotigotine is dopamine D2 and D3 receptor agonist. Ki values are 13 and 0.71 nM for D2 and D3 respectively. Rotigotine also has significant affinity for 5-HT1A and adrenergic ?2B receptors. Rotigotine exhibits antiparkinsonian acitivity.

Rotigotine hydrochloride
A3777-50 50 mg
EUR 360
Description: Rotigotine is dopamine D2 and D3 receptor agonist. Ki values are 13 and 0.71 nM for D2 and D3 respectively. Rotigotine also has significant affinity for 5-HT1A and adrenergic ?2B receptors. Rotigotine exhibits antiparkinsonian acitivity.

Rotigotine hydrochloride
A3777-500 500 mg
EUR 1663.2
Description: Rotigotine is dopamine D2 and D3 receptor agonist. Ki values are 13 and 0.71 nM for D2 and D3 respectively. Rotigotine also has significant affinity for 5-HT1A and adrenergic ?2B receptors. Rotigotine exhibits antiparkinsonian acitivity.

Tipiracil hydrochloride
A3875-10 10 mg
EUR 553.2
Description: Tipiracil is an inhibitor of Thymidine phosphorylase (TP). Thymidine phosphorylase (TP)is a key enzyme in the pyrimidine nucleoside salvage pathway.

Tipiracil hydrochloride
A3875-25 25 mg
EUR 774
Description: Tipiracil is an inhibitor of Thymidine phosphorylase (TP). Thymidine phosphorylase (TP)is a key enzyme in the pyrimidine nucleoside salvage pathway.

Tipiracil hydrochloride
A3875-5 5 mg
EUR 382.8
Description: Tipiracil is an inhibitor of Thymidine phosphorylase (TP). Thymidine phosphorylase (TP)is a key enzyme in the pyrimidine nucleoside salvage pathway.

Tipiracil hydrochloride
A3875-5.1 10 mM (in 1mL DMSO)
EUR 351.6
Description: Tipiracil is an inhibitor of Thymidine phosphorylase (TP). Thymidine phosphorylase (TP)is a key enzyme in the pyrimidine nucleoside salvage pathway.

Tipiracil hydrochloride
A3875-50 50 mg
EUR 1230
Description: Tipiracil is an inhibitor of Thymidine phosphorylase (TP). Thymidine phosphorylase (TP)is a key enzyme in the pyrimidine nucleoside salvage pathway.

Vandetanib hydrochloride
A3906-100 100 mg
EUR 517.2
Description: Description: IC50 Value: 40 nM (VEGFR2) [1]; 500 nM (EGFR) [2] Vandetanib is an anti-cancer drug that is used for the treatment of certain tumours of thethyroid gland.

Vandetanib hydrochloride
A3906-25 25 mg
EUR 201.6
Description: Description: IC50 Value: 40 nM (VEGFR2) [1]; 500 nM (EGFR) [2] Vandetanib is an anti-cancer drug that is used for the treatment of certain tumours of thethyroid gland.

Vernakalant Hydrochloride
A3915-10 10 mg
EUR 847.2
Description: IC50: Vernakalant inhibits two specific potassium currents, IKur (IC50 = 9 ??) and IKACh (IC50=10 ?M) which are only present in atrial myocardium [1].Vernakalant blocks atrial potassium channels, thereby prolonging repolarization.

Vernakalant Hydrochloride
A3915-100 100 mg
EUR 3316.8
Description: IC50: Vernakalant inhibits two specific potassium currents, IKur (IC50 = 9 ??) and IKACh (IC50=10 ?M) which are only present in atrial myocardium [1].Vernakalant blocks atrial potassium channels, thereby prolonging repolarization.

Vernakalant Hydrochloride
A3915-50 50 mg
EUR 2090.4
Description: IC50: Vernakalant inhibits two specific potassium currents, IKur (IC50 = 9 ??) and IKACh (IC50=10 ?M) which are only present in atrial myocardium [1].Vernakalant blocks atrial potassium channels, thereby prolonging repolarization.

Vilazodone Hydrochloride
A3919-10 10 mg
EUR 129.6
Description: Vilazodone (EMD 68843; SB 659746A; 5-{4-[4-(5-cyano-3-indolyl)-butyl]-1-piperazinyl}-benzofuran-2-carboxamide hydrochloride) is a combined serotonin specific reuptake inhibitor (SSRI) and 5-HT1A receptor partial agonist currently under clinical evaluation for the treatment of major depression.

Vilazodone Hydrochloride
A3919-5.1 10 mM (in 1mL DMSO)
EUR 129.6
Description: Vilazodone (EMD 68843; SB 659746A; 5-{4-[4-(5-cyano-3-indolyl)-butyl]-1-piperazinyl}-benzofuran-2-carboxamide hydrochloride) is a combined serotonin specific reuptake inhibitor (SSRI) and 5-HT1A receptor partial agonist currently under clinical evaluation for the treatment of major depression.

Vilazodone Hydrochloride
A3919-50 50 mg
EUR 157.2
Description: Vilazodone (EMD 68843; SB 659746A; 5-{4-[4-(5-cyano-3-indolyl)-butyl]-1-piperazinyl}-benzofuran-2-carboxamide hydrochloride) is a combined serotonin specific reuptake inhibitor (SSRI) and 5-HT1A receptor partial agonist currently under clinical evaluation for the treatment of major depression.

Voreloxin Hydrochloride
A3925-10 10 mg
EUR 895.2
Description: Voreloxin is a small molecule and a naphthyridine analogue with antineoplastic activity. Vosaroxin intercalates into DNA in a site-specific manner and blocks the re-ligation process carried out by topoisomerase II during DNA replication.

Voreloxin Hydrochloride
A3925-5 5 mg
EUR 656.4
Description: Voreloxin is a small molecule and a naphthyridine analogue with antineoplastic activity. Vosaroxin intercalates into DNA in a site-specific manner and blocks the re-ligation process carried out by topoisomerase II during DNA replication.

Voreloxin Hydrochloride
A3925-5.1 10 mM (in 1mL DMSO)
EUR 717.6
Description: Voreloxin is a small molecule and a naphthyridine analogue with antineoplastic activity. Vosaroxin intercalates into DNA in a site-specific manner and blocks the re-ligation process carried out by topoisomerase II during DNA replication.